Antipsychotic medication non-adherence among schizophrenia patients in Central Ethiopia
S. Afr. j. psychiatry (Online)
; 24: 1-6, 2018. ilus
Article
in English
| AIM
| ID: biblio-1270843
Responsible library:
CG1.1
ABSTRACT
Background:
Despite the fact that adherence to antipsychotic medications is the cornerstone in the treatment and prevention of relapse of the disease, non-adherence is a major problem among schizophrenia patients. The purpose of this study was to assess the magnitude and factors associated with antipsychotic medication non-adherence among schizophrenia patients in Amanuel Mental Specialized Hospital.Method:
An institution-based cross-sectional study was conducted among 412 people with schizophrenia at Amanuel Mental Specialized Hospital from April to May 2014. Non-adherence was assessed using the questionnaire of Morisky medication adherence rating scale and semi-structured questions for assessment of associated factors. Logistic regression analysis was used to assess predictors of non-adherence.Results:
Prevalence of non-adherence was 41.0% among schizophrenia patients. Living in rural areas (adjusted odds ratio [AOR] = 2.07; 95% confidence interval [CI] 1.31, 3.28), current substance use (AOR = 1.67; 95% CI 1.09, 2.56), long duration of treatment (AOR = 2.07; 95% CI 1.22, 3.50) and polypharmacy (AOR = 2.13; 95% CI 1.34, 3.40) were found to be significantly associated with non-adherence.Conclusion:
The results indicate that non-adherence to antipsychotic medication was a major problem among patients with schizophrenia. Reducing the number of antipsychotic medications and availing drugs in rural areas may decrease the level of non-adherence
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Index:
AIM (Africa)
Main subject:
Patients
/
Schizophrenia
/
Antipsychotic Agents
/
Ethiopia
Type of study:
Observational study
/
Prognostic study
/
Qualitative research
/
Risk factors
Country/Region as subject:
Africa
Language:
English
Journal:
S. Afr. j. psychiatry (Online)
Year:
2018
Type:
Article
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