Effect of oral midazolam in preventing postoperative emergence agitation in children
Sahel medical journal (Print)
; 22(1): 1-7, 2019. tab
Article
in English
| AIM
| ID: biblio-1271696
Responsible library:
CG1.1
ABSTRACT
Introduction:
Emergence from general anaesthesia can be complicated by the presence of agitation in children and thus presents a challenging situation for postanesthesia care providers. Several factors are associated with emergence agitation (EA). These include pain, preoperative anxiety, young age, poor adaptability, short time to recovery, among others.Objective:
This study aimed to determine the effect of oral midazolam inpreventing postoperative EA in children. Materials andMethods:
This was a casecontrol study carried out among 80 healthy children aged 110 years scheduled for daycase surgery. The children were randomly assigned to receive either a syrup of paracetamol 10 mg/kg with injectable midazolam 0.5 mg/kg added to the syrup (Group A) or a placebo in the form of paracetamol syrup (Group B) at a dose of 10 mg/kg 30 min before induction of anesthesia. Patients' state of agitation was assessed every 5 min for the 1st h by means of an EA scale. Children with an agitation score of 3 or 4 were classified as agitated.Prolonged agitation was defined as a score of â¥3 lasting 15 min after arrival in the recovery room. Data were analyzed using the Statistical Software for Social Sciences version 20.Results:
Eighty children aged 110 years were enrolled in the study. Majority of the procedures were circumcisions (48.75%), while urethral dilatation, examination under anesthesia, and tongue release were the least (1.25%). There was no statistically significant difference in the agitation state of the two groups (P = 0.60).Conclusion:
Premedication with oral midazolam 0.5 mg/kg administered 30 min preoperatively does not prevent EA in all cases
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Index:
AIM (Africa)
Main subject:
Midazolam
/
Child
/
Emergence Delirium
/
Anesthesia
Type of study:
Controlled clinical trial
/
Observational study
/
Risk factors
Language:
English
Journal:
Sahel medical journal (Print)
Year:
2019
Type:
Article
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