Pre-exposure Prophylaxis and Antiretroviral Therapy for HIV Prevention in South Africa which is the Best Use of Resources
Article
in English
| AIM
| ID: biblio-1272073
Responsible library:
CG1.1
ABSTRACT
An estimated 1.6 million new HIV infections occurred in 2012 in sub-Saharan Africa (1); highlighting the need for continued investments in HIV treatment and prevention efforts. With an HIV prevalence of about 18; South Africa (RSA) remains a particularly affected country; despite sustained investments in HIV control programs such as expansion of antiretroviral therapy (ART). In recent years; scientific innovations in HIV control have expanded the range of available interventions - male circumcision; topical microbicides; oral pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) have all sparked significant interest due to their potential effectiveness (ART reduces HIV transmission by up to 96; PrEP by more than 60) and versatility (circumcision is effective without additional actions required from the person; PrEP is meant for use by uninfected individuals; ART is given to infected individuals). While all these options are potentially available; resources remain limited and choosing which interventions to implement at scale is a difficult task; given the complex nature of disease transmission; the impact of behaviour in epidemic dynamics (number of partners; rates of condom use; adherence to treatment/prevention regimens); and the different costs of these programs
Full text:
Available
Index:
AIM (Africa)
Main subject:
Primary Prevention
/
HIV Infections
Type of study:
Risk factors
Language:
English
Journal:
South African Centre for Epidemiological Modelling and Analysis (SACEMA)
Year:
2014
Type:
Article
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