Osteogenesis imperfecta: a report of 3 cases in Uganda Africans

ABSTRACT

3 cases of osteogenesis imperfecta (0.1) seen at Mulago Hospital diagnosed as per clinical and X-ray appearances are presented. Case No. 1 is that of a neonate who died 6 hours and 20 min. after delivery. Postmortem X-rays were done confirming the clinical suspicion of 0.1 Case No. 2 an infant of 8 months was X-rayed because of weakness of lower limbs since 3 months of age. The films led to the diagnosis. The 3rd case with typical radiological features was retrieved from the departmental archieves and no history was available. The salient radiological features; namely cortical thinning; scanty spongiosa and multiple fractures; healing with scanty callus were common to all the three cases above. 0.1 is not an uncommon bone dysplasia in Uganda Africans