Oxidative stress and dyslipidaemia among ghanaian HAART-Naive HIV Patients and those on HAART
West Sfr. J. Pharm
; 22(1): 58-66, 2012. tab
Article
in English
| AIM
| ID: biblio-1273585
Responsible library:
CG1.1
ABSTRACT
"Background:
Pharmacogenomics/pharmacogenetics has the potential to mitigate adverse drug reactions and optimize pharmacotherapy in individuals. Over the past several years; there has been increasing attention towards the characterization of pharmacogenomic biomarkers in African populations; both locally and internationally. However; the perceptions of the African health care community towards pharmacogenomic testing have not been studied.Objectives:
To assess knowledge and perceptions of pharmacogenomics among health care professionals in Benin City; Nigeria.Methods:
In this preliminary and pilot investigation; we used a semi-structured qualitative survey methodology to understand the perceptions of pharmacists and pharmacologists towards pharmacogenomics in an academic care centre in Benin City; Nigeria. Three themes were explored Knowledge and experience with pharmacogenetics; Expectations about how a pharmacogenetic testing service could be used; and Capacity building for pharmacogenetic service delivery.Results:
Though none of the participants had received training or undertaken research in pharmaco-genomics; all participants were familiar with the field and listed beneficial outcomes associated with pharmacogenetic testing. Participants identified factors such as lack of funding; infrastructure; and manpower for limitations of pharmacogenomic testing in Nigeria. Participants listed numerous ethical issues and concerns in recruiting participants for research and introducing pharmacogenetics in the clinic; including the need to ""win the confidence of the people.""Conclusion:
Pharmacists and pharmacologists in an academic centre in Nigeria are aware of the benefits of pharmacogenomics; but cite many hurdles to overcome before this field can become a routine part of patient care in their communities."
Full text:
Available
Index:
AIM (Africa)
Main subject:
Cross-Sectional Studies
/
Oxidative Stress
/
Antiretroviral Therapy, Highly Active
/
Dyslipidemias
/
Ghana
/
Liver Diseases
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
/
Qualitative research
/
Risk factors
Country/Region as subject:
Africa
Language:
English
Journal:
West Sfr. J. Pharm
Year:
2012
Type:
Article
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