Vitamin d status in children with acute lymphoblastic leukemia
Zagazig univ. med. j
; 25(6): 960-966, 2019. tab
Article
in English
| AIM
| ID: biblio-1273881
Responsible library:
CG1.1
ABSTRACT
Background:
Skeletal morbidities are a common initial presentation and outcome in acute lymphoblastic leukemia(ALL). Vitamin D plays a vital role in the physiological regulation of calcium and phosphate transport and bone mineralization. Also high (25(OH)) level and high vitamin d intake at the time of diagnosis and initiation of anticancer treatment were associated with improved outcome.Methods:
Twenty five ALL patients admitted to hematology and oncology unit, children hospital Zagazig University in one-year .vitamin D (25 (OH)) level was assessed in all patients at diagnosis. Patients were classified into deficient vitamin D (0-20)ng/ml , insufficient vitamin D (20-30)ng/ml and sufficient vitamin D (30-50)ng/ml. Statistical analysis was done to determine relation between different groups and ALL patients characteristics.Results:
Vitamin D deficient in 24% of patients, vitamin D insufficient in 48% of patients, and vitamin D sufficient in 28% of patients. There was high statistical difference between different groups regarding bone pain and sex.Conclusions:
A non-sufficient level in childhood all (deficiency and insufficiency) is common in childhood ALL and this is related to bone pain as initial clinical presentation. Vitamin D is related to presentation and prognosis of ALL in children
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Index:
AIM (Africa)
Main subject:
Bread
/
Leukemia
/
Egypt
Type of study:
Prognostic study
Country/Region as subject:
Africa
Language:
English
Journal:
Zagazig univ. med. j
Year:
2019
Type:
Article
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