Occurrence of high level methicillin resistance Staphylococcus aureusin patients from health facilities in Akwa Ibom State, Nigeria
Ibom Medical Journal
; 17(1): 56-61, 2024.
Article
in English
| AIM
| ID: biblio-1552049
Responsible library:
CG1.1
ABSTRACT
Background:
Methicillin resistant S. aureus(MRSA) has become a major public health predicament worldwide. This is owing to its involvement in the evolution of MDR strains and difficulty in therapeutic management of infected patients. This study was conducted to investigate the prevalence of methicillin resistance Staphylococcus aureusamong patients in two health facilities in Akwa Ibom State, Nigeria.Materials andMethods:
Clinical isolates of patients from University of Uyo Teaching Hospital (UUTH), Uyo and General Hospital, Ikot Abasi (GHIA) were investigated based on the strategic location of the hospitals. The study design was a descriptive cross-sectional study. Three hundred clinical samples were collected from male and female in and out-patients of all ages and processed using standard bacteriological methods. Detection of Staphylococcus aureusand MRSAstrains were done according to standard protocols while antibiotic susceptibility testing of MRSAisolates was conducted using Kirby-Bauer disc diffusion method and interpreted following the CLSI 2021 guidelines.Results:
The prevalence of MRSAstrains in this study was 42.9%. Majority of patients with MRSAwere from UUTH (44%) closely followed by patients from GHIA(40%). High antibiotics resistant rates of MRSAwere recorded for ampicillin (96.6%), ciprofloxacin (73.3%), erythromycin (63.3%) and cotrimoxazole (60%). Gentamicin and ceftriaxone sensitivity rates were 53.3% and 63.4%, respectively.Conclusion:
Health facilities in the state should institute effective antimicrobial stewardship, intensify surveillance and screening of Staphylococcus aureusfor MRSAstrains to guard against dissemination of multidrug resistant strains in both hospital and community settings because of the clinical implications.
Fulltext
- https://ibommedicaljournal.org/index.php/imjhome/article/view/378/1026
- https://indexmedicus.afro.who.int/iah/fulltext/Occurrence of high level methicillin resistance Staphylococcus aureusin patients from health facilities in Akwa Ibom State, Nigeria_Bawonda E O.pdf
- https://fi-admin.bvsalud.org/document/view/npqba
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Index:
AIM (Africa)
Main subject:
Staphylococcus aureus
/
Prevalence
/
Methicillin-Resistant Staphylococcus aureus
Language:
English
Journal:
Ibom Medical Journal
Year:
2024
Type:
Article
Institution/Affiliation country:
Department of Medical Microbiology and Parasitology, Faculty of Basic Clinical Sciences, University of Uyo, Uyo, Nigeria/NG
/
Institute for Biomedical Research and Innovations, College of Health Sciences, University of Uyo, Uyo, Nigeria/NG
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