Cyclopia with polydactyly and congenital heart disease in one of discordant twins: acase report

Cyclopia is a rare congenital abnormality consisting of fused orbits and a single eye and is the most extreme form of alobar holoprosencephaly. It is an uncommon congenital anomaly resulting from arrest of the development of the anterior end of the neural plate. It is always associated with abnormalities of the brain. In one study, cyclopia was reported in one discordant twin only[1]. In this report, we describe a case of cyclopia that was associated with ploydactyly and congenital heart disease in a female infant who was one of discordant twins

result of 88 cycles of IUI in 75 infertile couples at 2001-2003 in Amir-Al-Momenin hospital

Intrauterine insemination with or without super ovulation has been proposed for the treatment of certain reproductive problems, Including male Sub Fertility, poor cervical mucus, presence of anti-sperm antibodies, minimal or mild endometriosis, and ovulation disorders refractory to previous attempts for ovulation and unexplained in fertility. To compare the pregnancy rates achieved by IUI in this center with other centers. A descriptive study in 88 cycles of 75 infertile couples during 2 years [2001 - 2003]. 67 cycles stimulated with HMG+ CC and 21 cycles with CC alone. The patients divided to 4 groups according to cause of infertility; G1: anovulatory, G2: male, G3: anovulatory + male and G4: unexplained. Pregnancy rate was 16% per patient and 13.6% per cycle of 12 pregnancies, 6 were Term deliveries, 2 ongoing, 2 abortions, 1 IUFD, 1 pre-term and 1 Twin Pregnancy. This study didn't show a statistical significant difference between HMG+ CC and CC cycles [P>0.85] and no differences existed between pregnancy rates in different causes of infertility. [0.1 < P < 0.2]: As in 67 cycles, HMG+CC has been used to stimulate the ovulation and the mean of using HMG has been 10, so this method can be used for the people who didn't have any suitable response to CC and also for the people due to having OHSS, fear to use HMG. And consequently, the consumption rate [HMG] can be reduced