[Multiple myeloma in young patients]

Multiple myeloma is the most common type of malignant hemopathy, affecting mainly the elderly; the occurrence in adolescents and young adults remains exceptional. This is a 5-year retrospective study conducted at the Hematology Laboratory of the CHU Hassan II in Fez, including 13 patients with multiple myeloma whose age is less than or equal to 40 years. The average age of patients is 35.5 years, with a male predominance. The clinical signs are dominated by bone signs. The biological assessment shows a monoclonal gamma peak in 60% of cases, and renal failure in 38% of cases. Sternal puncture showed plasma cell infiltration in 30% of cases. 45% of the patients were treated by CDT, 55% by VDT, with good progress in 30% of cases over an average of 60 months. This study shows that myeloma in young people is marked by its clinical severity, but the therapeutic advances made it possible to improve the prognosis of the patients

[ status of vitamin D of patients hospitalized at CHU Hassan II of Fes]

This is a retrospective study of 8349 patients admitted to the various departments of CHU Hassan II of Fès, from 01/01/2017 to 31/12/2017. The vitamin D assay was performed by a chemiluminescent immunological technique [CMIA]. The normal value of vitamin D is defined by a serum level higher than 30 ng/ml, the deficiency is defined by a serum level between 10 and 30 ng/ml, we distinguished between 20 and 29 : moderate insufficiency, and between 10 and 20: significant insufficiency and deficiency is confirmed by a rate below 10 ng / ml. The mean age was 48,74 ± 18,18 years old. This is 73.4% women and 26,6% men. Only 15% of patients had sufficient levels of vitamin D. 63% of patients had a deficiency, while 22% had a deficiency. The results of this study show that deficiency and vitamin D deficiency are very common despite the sunshine of the region of Fez