Nutritional anaemia is predisposing factor for hair loss among Egyptian female students Intervention [part II]

This intervention study was conducted on 220 Egyptian female students suffering from hair loss. Age of the students ranged from 12 to 18 years, all student groups [case + control = 340] were subjected to an interviewing questionnaire. All students were subjected to careful history taking, physical examination, dermatological examination and blood analysis. The diseased females [220] were given iron supplementation in a dose 6 mg elemental iron/kg/day divided into 2-3 doses between meals for 6 months. The interval was 6 months extending from the beginning of May 2002 to the end of October 2002. After this period all females subjected to revised careful history taking, physical examination, dermatological examination and blood analysis. The study revealed the highest negative correlation coefficient between the percent of Hb, iron and ferritin and the percent of number of hair falling/day. The results showed the highest positive correlation coefficient between the percentage of Hb, ferritin and iron and the percent of hair density. Also, the study revealed positive correlation coefficient between the level of Hb, ferritin and iron and% of hair growth

Biomonitoring of pesticides formulators: frequency of micronuclei, protein carbonyls, epidermal growth factor and basic fibroblast growth factor

The frequency of micronucleus formation [FMN] in circulating lymphocytes, plasma basic fibroblast growth factor [bFGF], epidermal growth factors [EGF] and protein carbonyls [CP] was measured in the blood of 25 pesticide [fenvalerate and deltamethrin] manufacture exposed workers versus 20 controls. The pesticide workers showed an increase in the levels of the FMN [4.8 +/- 4 vs. 3 +/- 1.1%, t = 2.14], bFGF [6.3 +/- 4.9 vs. 1.9 +/- 1.36 ng/ml] and EGF [4.8 +/- 1.5 vs. 1.02 +/- 0.2 ng/ml] and PC [0.9 +/- 0.4 vs. 0.54 +/- 0.2]. It can be concluded that the occupational exposure to pyrethroid pesticides during formulation induces an oxidative stress that can consequently induce genotoxicity

Nutritional anemia as a pedisposing factor for hair loss among Egyptian female students

A case control study was carried out in Ebn-Sander Health Insurance clinics [Eastern Cairo], which provide health service and medication to the schools, including El-Zeitoun, Kobry El-Kobba, Hamamat El-Kobba and Manshiet El-Bakry. They were selected for their cooperation and the availability of comprehensive health file system. A total of 220 female students suffering from hair loss [alopecia], their age ranged from 12 to 18 years were compared with 120 sibling females as an apparent normal control group. The interval was seven months extending from the beginning of October 2001 to the end of April 2002. All the studied groups [340 female students] were subjected to an interviewing questionnaire. The questionnaire was filled out with one attending parent under the supervision of the study members. The data about personal history, socioeconomic status, consumption of selected dietary items, associated symptoms with hair loss and parasitic infestation were gathered. The exclusion criteria of the study included the presence of chronic systemic diseases, surgery, trauma, congenital anomalies, bleeding tendency and renal or hepatic failure. All the studied groups were subjected after careful history taking to physical examinations and dermatological examination, urine, stool and hematological analysis

Angiolymphoid hyperplasia with eosinophilia and Kimura's disease: a clinicopathological study

In this work, the clinical and histopathological features of 10 cases of angiolymphoid hyperplasia with eosinophilia and 5 cases of Kimura's disease are described and a comparison between the features of the two lesions is presented. Angiolymphoid hyperplasia showed exuberant proliferation of vessels lined by plump endothelial cells with irregular nuclei and cytoplasmic vacuoles, together with fibromyxiod matrix and inflammatory cells infiltrate containing eosinophils. Involvement of muscular coat of blood vessels or even growth entirely within a vessel was a common feature. It occurred in the skin and subcutaneous tissue. Kimura's disease occurred in the parotid gland and the subcutaneous tissues. It was characterized by florid lymphoid infiltrate with prominent lymphoid follicle, vascularization of germinal centres, germinal centre necrosis with eosinophilic material [folliculolysis], and marked eosinophilia with or without eosinophil abscess formation

Tumour markers quantitation in pleural effusion

The aim of this study is to measure the concentrations of the tumour. markers: Carcinoembryonic antigen [CEA], alpha1 acid glycoprotein [AGP] and B[2]- microglobulin [B2 - m] both in serum and pleural fluid of patients with pleural effusion to illucidate the aetiogenesis of this effusion. Serum and pleural fluid samples, collected from 15 patients with malignant effusion and 15 patients with non malignant effusion [due to liver cell failure, congestive heart failure, tuberculosis or post-pneumonic effusion] were subjected to quantitative determination of these markers. Serum, and pleural fluid values of CEA and B2-m were significantly higher in malignant cases when compared with the non malignant ones [serum CEA levels were 18. 0 +/- 5 .2 ng/ml: mean +/- SEM versus 0.8 +/- 0. 3 ng/ml; P < 0.01 and pleural CEA concentrations were 16.4 +/- 5.3 ng/ml versus 2.3 +/- 1 .0 ng/mI; P < 0. 01 respectively Serum B2-m levels were 7. 5 +/- 1. 1 mg/L versus 2.3 +/- 0.3; P < 0. 05 while pleural fluid values were 2.8 +/- 0.4 mg/L versus 1 .5 +/- 0. 3 mg/L; P < 0.05 respectively]. Serum and pleural alpha[1] AGP levels showed no significant difference between malignant and non malignant conditions [Table 1]. In conclusion, there was significant association between malignancy and raised serum or pleural fluid values of both CEA and B[2]-m