Toxoplasmosis in a group of glucose-6-phosphate dehydrogenase deficient patients

This was a retrospective study that aimed at evaluating the relative risk of Toxoplasma infection in patients with glucose-6-phosphate dehydrogenase deficiency as compared to a control group with no glucose-6-phosphate dehydrogenase deficiency. Ninety-one blood donor volunteers had serology testing from Toxoplasma gondii and were screened for glucose-6-phosphate dehydrogenase deficiency by a qualitative method using fluorescent spot test. They were all males and their ages ranged from 17 to 52 years. Fifty-three persons [58%] were glucose-6-phosphate dehydrogenase deficient and 38 [42%] were glucose-6-phosphate dehydrogenase normal. In the glucose-6-phosphate dehydrogenase deficient group, 31 [58.5%] had positive titers for Toxoplasma; while in the glucose-6-phosphate dehydrogenase normal group 9 persons [24%] had positive titers for Toxoplasma. The relative risk of infection was 2.5 times more in the glucose-6-phosphate dehydrogenase deficient group, a statistically significant difference with a p value of 0.002. Glucose-6-phosphate dehydrogenase deficiency seems to increase the risk for Toxoplasma infection by 2.5 fold probably due to decreased killing effect, of phagocytic cells

Local effects on sensory nerves using two different treatment modalities

The present study was mainly based on comparing the effect of cryosurgery and soft laser on the mental nerve in dogs both histologically and histochemically. Autopsies were taken at the intervals of 7, 14 and 40 days postoperatively. The results demonstrated that, both modalities had in common the preservation of the gross morphology of the nerve thus allowing only temporary degeneration. However, the local destruction was more extensive in case of cryosurgery. Cryosurgery is indicated as analgesia in treatment of intractable facial pain, such as trigeminal neuralgia. Further indication include destruction of benign lesions. Laser can be used as analgesia in cases of aphthae, postoperatively following surgery, in cases of myofacial pain dysfunction syndromes

role of ultrasonography in diagnosis of orofacial lesion: clinico pathological correlation

Ultrasonography was used in conjunction with clinical examination in diagnosis of oro-facial lesions in eight different cases presented to the role surgeon. Accordingly, the surgical approach could be properly planned and histopathological study confirmed the clinical and ultrason-orgaphic findings. The ultrasoungraphy poved to be important in evidently differentiating between cystic, solid, benign and malignant lesions as well as the proximity of the mass to anatomical structures and actual cross sectional measurement of the lesion. The information obtained from ultrasonography could be superior to that obtained by plain and contrast radiography and is less invasive and less expensive that computerized axial tomography

Histopathologic and immunohistopathologic evaluation of Pityriasis rosea

Biopsy specimens of secondary skin lesions of PR obtained from 20 patients were studied histopathologically and immunohistopathologically [using monoclonal antibodies directed against the dermal inflammatory infiltrate]. The tissue was paraffin embedded after fixation in BS and methanol 13 cases only gave positive results.Still the pattern of monoclonal expression in the stained cases varies. Our results suggest a possible role that may be mediated by the cellular immune reaction in the pathomechanism of such disease

Role of blood flow in the treatment of orofacial infection in controlled diabetic patients

Thirty controlled diabetic patients were selected from the Outpatient Clinic of Faculty of Dentistry, Alexandria University. They suffered from oro-facial infection and cellulitis, and were divided into, three groups; each of which composed of 10 patients. One group treated with hostacycline alone, the second group treated with hostacycline and trental, and hotacycline and adalat were used for treatment of the third group. Swelling and pain were recorded and measured. Peripheral vascular resistane of each patient was also evaluated before treatment, and after 2, 4, 6, 8, and 10 days respectively. From this study, the following was concluded: 1. Adalat was the best one, when used together with hostacycline in the treatment of infected diabetic cases. 2. The use of trental and hostacycline in the treatment of infected diabetic cases was less effective than the use of adalat and hostacycline, but also assist in the treatment. 3. Hostacycline was suggested to be the least measure for effective treatment. So, it is better to use durgs for lowering the peripheral vascular resistance of the patient, in turn, blood flow will increase