1.
J Genet
;
2008 Dec; 87(3): 265-9
Article
in English
| IMSEAR
| ID: sea-114353
Subject(s)
Adult , Age of Onset , Aryl Hydrocarbon Hydroxylases/genetics , Base Sequence , Cytoskeletal Proteins/genetics , DNA Mutational Analysis , Eye Proteins/genetics , Female , Glaucoma, Open-Angle/enzymology , Glycoproteins/genetics , Humans , India/epidemiology , Male , Molecular Sequence Data , Mutation/genetics
2.
J Indian Med Assoc
;
2004 Dec; 102(12): 708, 710, 712 passim
Article
in English
| IMSEAR
| ID: sea-105885
ABSTRACT
Glaucoma is the second largest blinding disorder, after cataract, affecting about 67 million people worldwide. In India about 1.5 million people are blind due to glaucoma. Primary open angle glaucoma is the major sub-type of glaucoma affecting all ages and is genetically complex. Myocilin and optineurin are two different genes that have been implicated for primary open angle glaucoma. This review is focused on the studies being conducted in India on primary open angle glaucoma to identify the molecular defects and new directions undertaken using bioinformatic approaches towards a better understanding of the disease.
Subject(s)
Blindness/etiology , Chromosomes, Human, Pair 10/genetics , Computational Biology , Cytoskeletal Proteins/genetics , Eye Proteins/genetics , Glaucoma, Open-Angle/classification , Glycoproteins/genetics , Humans , India , Transcription Factor TFIIIA/genetics , Vision Disorders/etiology
3.
Indian J Ophthalmol
;
2003 Sep; 51(3): 279-81
Article
in English
| IMSEAR
| ID: sea-70685