Becker's nevus with ipsilateral breast hypoplasia: a case report and review of literature

Specific cutaneous associations in patients with Becker's nevus have been reported. We present a patient with typical clinical and histopathological features clearly consistent with Becker's nevus associated with ipsilateral breast hypoplasia. The changes were distinct and could be separated from smooth muscle hamartoma. We include clinical and histological illustrations of our case.

Fixed drug eruption: a descriptive study of 100 cases

Fixed drug eruption [FDE] is one kind of drug rashes that is characterized by re-appearance of the lesions on the same sites after re-exposure to the causative drug. This study was performed to evaluate the epidemiologic characteristics of FDE. This descriptive study was done on a series of 100 FDE cases, who were admitted at the outpatient dermatology clinic of Hazrat-e-Rasoul Hospital over a six-year period. The primary diagnosis of FDE was suggested according to clinical findings including a remaining hyperpigmentation at the site of healed skin lesion [s]. Oral challenge test with a single low dose administration of the suspected drug was used to confirm the diagnosis. Recurrence of the lesion [s] at the same body area [s] was considered as positive result. Most commonly causative agents were co-trimoxazole and codein, which were found in 88% and 3% FDE cases; respectively. The most common site of involvement was penile glans in 57.7% of male patients and trunk in 48.3% of females. In one patient, reaction to multiple drugs including co-trimoxazole, codein and tetracycline was observed and after re-challenge with each drug, re-appearance of the skin lesion at the same site was evident. Several patients reported concomitant acetaminophen intake, but there was no reaction to that drug. Co-trimoxazole is the most common cause of FDE