1.
Indian J Exp Biol
;
1997 Aug; 35(8): 822-4
Article
in English
| IMSEAR
| ID: sea-56207
ABSTRACT
Antiestrogens affect spermatozoa through their action on Leydig and Sertoli cells. Direct effect of antiestrogens namely tamoxifen and centchroman in concentration of 1, 2.5, 5, 10 and 20 micrograms/ml in incubation medium was determined on motility and penetration ability of human spermatozoa. Motility (%) was invariably reduced after 15, 30 and 60 min. of incubation. Addition of 17 beta-estradiol to medium with antagonist caused inhibition of motility in dose related manner. The distance travelled by spermatozoa treated with tamoxifen or centchroman in media was reduced by 30% and addition of estradiol along with antiestrogen reduced it to 50% compared to that of untreated spermatozoa.
Subject(s)
Adult , Centchroman/pharmacology , Estradiol/pharmacology , Estrogen Antagonists/pharmacology , Female , Humans , Male , Sperm Motility/drug effects , Sperm-Ovum Interactions/drug effects , Tamoxifen/pharmacology
2.
Indian J Exp Biol
;
1984 Jul; 22(7): 363-6
Article
in English
| IMSEAR
| ID: sea-59596
3.
Article
in English
| IMSEAR
| ID: sea-21950
Subject(s)
Adult , Estrogens/urine , Female , Humans , Intrauterine Devices, Copper , Pregnanediol/urine
4.
Indian J Exp Biol
;
1977 Dec; 15(12): 1177-81
Article
in English
| IMSEAR
| ID: sea-55638
Subject(s)
Adult , Benzopyrans/therapeutic use , Centchroman/pharmacology , Humans , Male , Oligospermia/drug therapy , Spermatozoa/drug effects
5.
Article
in English
| IMSEAR
| ID: sea-22417
6.
Article
in English
| IMSEAR
| ID: sea-19333
Subject(s)
Adrenal Cortex Hormones/urine , Adult , Estrogens/urine , Female , Humans , India , Ovarian Diseases/urine , Progestins/urine
7.
Article
in English
| IMSEAR
| ID: sea-21296