[Childhood cutaneous tuberculosis: about 9 cases]

Tuberculosis is still endemic in developing countries. In Morocco, thirty thousand new cases are recorded each year, cutaneous localization represents 1, 4 per cent. The aim of this work is to study the epidemiological, clinical and therapeutic features of childhood cutaneous tuberculosis in Morocco. Patients and methods: It is a retrospective study including all cases of childhood cutaneous tuberculosis hospitalized in the dermatology department of the Ibn Sina hospital in Rabat, over a 11 years period. Results: Nine cases were collected. The mean age was 14 years. The clinical features are as follows: gumma [5 cases], scrofuloderma [3 cases], lupus vulgaris [1 case]. The Mantoux test was positive in 88 per cent, tuberculoid granuloma was observed in all the cases. All children responded to antimycobcterial chemotherapy. Conclusion: Gumma and scrofuloderma were the commonest forms found in Moroccan series

Children scleroderma: a retrospective study of 25 cases

Scleroderma is uncommon in childhood. The aim of our study was to analyse the frequency of different clinical forms, their prognostic significance and to assess the pertinence of therapeutic options. Patients and method: It is a retrospective study concerning 25 cases of scleroderma in childhood and colliged in the Dermatology Unit of Rabat Ibn-Sina University Hospital Center between 1985 and 2003, excluding patients older than 15 year-old. Localized scleroderma was observed in 18 children and diffuses lesions in 7 children. Localized scleroderma began at a mean age of 10 year-old. The lesions were isolated bands [44%], associated with morphea [11%], or multiple morphea [11%]. Mean duration of the clinical course was longer in cases with more and deeper lesions. Eosinophilia was observed in 11% of cases and antinuclear antibodies were found in 22% of cases. Local and general corticosteroids appeared to be efficient in superficial and active lesions. Diffuse scleroderma began at mean age of 11 year-old. The therapeutic problems were similar to those in adults. In conclusion, scleroderma prognosis depends on functional impairment resulting from major sequelae of localized forms and the life-threatening situations occuring in systemic forms

dermatite atopique: aspects physiopathologiques et traitement

Atopic dermatitis represents the cutaneous facet of atopic disease. Its prevalence is in a regular increase these last decades. The physiopathology of this dermatitis is complex and not well known, implicating genetic, immunological, biochemical and environmental factors. The onset of Atopic dermatitis can start at any age of life. But it is exceptional before the age of two months; in the same way its onset after 20 years is relatively rare. It is an extremely polymorphous affection in its clinical expression that depends on the age of the subject, which necessitates establishment of diagnostic criteria. In spite of being benignity, atopic dermatitis is a chronic disease affecting negatively the quality of life of the majority of patients. The symptomatic treatment is based on topical corticosteroids and moisturizers. However, a better knowledge about its pathogenesis allows to hope for a therapeutic approach by immunomodulators, especially for the serious cases

Sporothrix schenkii: a double face fungus

Sporotrichosis is a rare profound mycosis exsisting in a sporadic state in Morocco. A calrification of this disease is proposed. A general review on sporotrichosis was performed using Medlines data base, the articles published during the last ten years were analyzed. We gave priority to works dealing particularly with the biological aspects of the mycosis. The particular biotope of the parasitic development and its mode of contamination explain its rarity in Morocco. According to the fungal way of penetration and the immune state of the host, 4 clinical forms were described: the lymphocutaneous, pure cuteneous, pulmonary and disseminated form. As the direct examination exceptionally visualizes the spors, culture on Sabouraud medium was performed to do a mycological diagnosis which approved the presence of fine and ramified myceliums. Treatment depends on the clinical forms: itraconazale in the cutaneous and osteo-articular sporotrichosis and the amphotaricin B in the pulmonary form

Systemic lupus erythematosus

Bullous lesions are very rarely observed during systemic erythematosus lupus [S.E.L.]. In this paper we discuss the association between S.E.L and auto-immune bullous diseases. Is it a real bullous S.E.L or an association of S.E.L + auto- immune bullous disease

Carcinome epidermoide de la levre inferieure sur cicatrice de lupus erythemateux chronique: premier cas marocain

Some cases of skin cancer developping from erythematous chronic lupus were published among the world. We make know our experience about a case of a patient suffering with a chronic erythematous lupus with a lip cancer that were developping from this mucous localisation

Sarcoid reaction on a tattoo-four observations two of them with systemic affection

Four cases of sarcoidal granuloma in tattoos, occurring in the setting of two systemic sarcoidosis are presented. All these cases were observed in women and there is a long time between tattooing [in childhood] and the development of sarcoidal reaction on the skin [over 40 years]. Skin sarcoidosis is very resistant, to treatment, and it is important to oversee the patients to look for systemic sarcoidosis