Alelos HLA DQ alfa maternos, pérdida recurrente del embarazo y síndrome de anticuerpos antifosfolípidos

Autoantibodies to phospholopids antigens APL, are associated with a history of RSA in women without autoinmunedisease. APL interfere with the production of prostaciclin allowing the increase of thrombotic events. Phospholipids are compounds of placental mebrane structure and also they have been considered as an adhesion molecules participating in the formation of syncytotrophoblast. Trophoblastic antigens can induce the production of antiphospholipids antibodies. This antiboidies can delay the trophoblast development by the action in the adhesion molecules. We have studied 270 women with RSA and 31 women as a control group which had normal pregnancies. The testing incluided antiphospholopid antibodies and genetic evaluation of class II DQ antigens of the couple. We have showed APL titles no gretaer than 1/25 in normal pregnant women. In RSA the incidence increases in a fifteen percent with each subsequent pregnancy loss. We observed an strong correlation between maternal HLA DQ alfa 4.1 (0501) and increases in APL titles in patients who loss their pregnancy again

Queimadura extensa na vigencia de gravidez. / Extensive burn in pregnancy

Os autores relatam o caso de uma paciente de 24 anos, gravida na 14a. semana e com extensa area corporal queimada, perfazendo uma superficie de 54,8%. Salientam que o tratametno realizado, foi baseado apenas nos dados clinicos e laboratoriais deixando de labo as formas classicas de hidratacao do grande queimado, pois tratava-se de gestante e, portanto, apresentava alteracoes hemodinamicas peculiares. O prognostico foi favoravel tanto para o feto que nasceu prematuro, mas dentro dos padroes da normalidade, quanto para a mae que sobreviveu

Routine methods in Bacteriology of tuberculosis and the functionsof the laboratory service in the National Tuberculosis Programme

Than-Tin, Ma and A.G. Beer. Routine menthods in bacteriology of tuberculosis and the functions of the laboratory services in the National Tuberculosis Programme.Union of Burma J. Life Sci.(1973) 6, 67-71. A general outline of the laboratory services is given and its research activities and routine bacteriological procedures are described. The role of the laboratory services in the Tuberculosis Control Programme in the context of integration of the latter into the basic health services is discussed.

Evalution methods of the National Tuberculosis Control Programme, Burma

The evaluation process as applied to tuberculosis control programmes and its methodology in respect of epidemiological, operational and technical assessmentsare defined and clearly explained. Detials of planning the evaluation and of assessing the objectives, activities and resources of each of the 3 components of the NTP namely-Prevention, Case-finding and Treatment, are gone into, and the methods of setting up forecasts (or target indices) of the NTP and of undertaking acomprehensive operational assessment (which is applied to all three programme components) are outlined.