Subject(s)
Aged, 80 and over , Female , Humans , Male , Middle Aged , Intracranial Embolism , Middle Cerebral Artery , Stroke/etiology , Vascular Calcification/complications , Aortic Valve/surgery , Coronary Artery Bypass/adverse effects , Heart Valve Prosthesis Implantation/adverse effects , Intracranial Embolism/complications , Intracranial Embolism , Middle Cerebral Artery , Tomography, X-Ray Computed , Vascular CalcificationSubject(s)
Humans , Male , Middle Aged , Carcinoma, Renal Cell/secondary , Cranial Nerve Neoplasms/secondary , Kidney Neoplasms , Trigeminal Nerve Diseases/etiology , Carcinoma, Renal Cell/diagnosis , Cranial Nerve Neoplasms/diagnosis , Disease Progression , Magnetic Resonance Imaging , Neoplasm Invasiveness , Tomography, X-Ray Computed , Trigeminal Nerve Diseases/diagnosisABSTRACT
Central nervous system (CNS) cavernous malformations (CMs) are developmental malformations of the vascular bed with a highly variable clinical course due to their dynamic nature. We present one case of "de novo" brainstem cavernous malformation after radiation therapy adding to the increasing number of reported cases in the medical literature, and the case of a pregnant patient with symptomatic intracranial hemorrhage related to brainstem CMs to illustrate the complex nature in management of these patients, followed by a review of clinical and radiographic characteristics. CMs account for 8-15 percent of all intracranial and intraspinal vascular malformations. Although traditionally thought to be congenital in origin, CMs may present as acquired lesions particularly after intracranial radiation therapy. Clinical manifestations are protean and surgical treatment should be considered for patients with progressive neurologic deficits.
Malformações cavernosas (MFC) do sistema nervoso central são malformações do desenvolvimento do leito vascular com múltiplas apresentações clínicas devido a sua natureza dinâmica. Apresentamos dois casos de malformações cavernosas do tronco cerebral: o primeiro após radioterapia e o segundo em paciente grávida com hemorragia intracraniana sintomática. MFC são responsáveis por cerca de 8-15 por cento de todas as malformações vasculares. Embora tradicionalmente sejam genéticas, as MFC podem também ser adquiridas, particularmente após radioterapia. As manifestações clínicas são variáveis e o tratamento cirúrgico deve ser considerado para pacientes com quadros neurológicos progressivos.
Subject(s)
Adult , Female , Humans , Middle Aged , Pregnancy , Brain Stem , Cerebral Hemorrhage/etiology , Intracranial Arteriovenous Malformations/diagnosis , Pregnancy Complications, Cardiovascular/diagnosis , Astrocytoma/radiotherapy , Cerebellar Neoplasms/radiotherapy , Intracranial Arteriovenous Malformations/etiology , Magnetic Resonance Imaging , Radiotherapy/adverse effectsSubject(s)
Humans , Brain Ischemia/classification , Brain Ischemia/complications , Brain Ischemia/diagnosis , Brain Ischemia/drug therapy , Brain Ischemia/epidemiology , Brain Ischemia/etiology , Brain Ischemia/mortality , Brain Ischemia/pathology , Brain Ischemia/physiopathology , Brain Ischemia/therapy , Cerebrovascular Disorders/diagnosis , Ischemic Attack, Transient/diagnosisSubject(s)
Intracranial Embolism and Thrombosis/etiology , Cerebral Infarction/etiology , Arteriosclerosis/complications , Cerebral Angiography , Intracranial Embolism and Thrombosis/diagnosis , Intracranial Embolism and Thrombosis/epidemiology , Cerebral Infarction/prevention & control , Heart Diseases/complications , Heart Diseases/diagnosisABSTRACT
El ACV isquémico es una de las causas más frecuentes de muerte e invalidez. A pesar de su alta incidencia, el manejo del ACV agudo sigue siendo controvertido. La mayoría de las formas corrientes de terapéutica están diseñadas para reducir las complicaciones de un ACV reciente o prevenir recidivas.Los datos experimentales sugieren que el tiempo óptimo para la intervención terapéutica debería situarse en las horas inmediatas posteriores a la isquemia cerebral