Influence of controlled diet on carbohydrate and lipid in diabetic patients

Three groups [each of ten] of newly detected non-insulin dependent diabetic patients were used in this study. The first group [group zero] was uncontrolled [received no treatment]. The second group [group A] was fed control diet ranging between 1500-2000 calories per day for two weeks. The third group [group B] was treated exactly as group A, then kept for another two weeks on the same control diet plus 30 g of wheat bran per day. On termination of treatment, fasting blood samples were taken for estimation of glucose, insulin, triglycerides and cholesterol. Moreover, blood samples were collected 30, 60 and 150 minutes following breakfast for glucose and insulin determination. It has been found that glucose and insulin levels were significantly decreased in group A of patients while their levels showed highly significant decrease in group B compared to the first uncontrolled group. Similar pattern was noticed for triglycerides and cholesterol where their levels were almost significantly decreased in groups A and B. The decrease was more apparent in group B where control diet contained wheat bran. Therefore, it is recommended for non-insulin dependent diabetic patients to maintain on control diet and to increase their intake of naturally rich sources of dietary fibers as raw vegetables, whole fruits and cereal grains in order to achieve better control of their diabetic state

Variation of prostaglandins output in response to variation in electrolyte intake

This investigation is concerned with the effect of different salt levels [Normal, High and Low] diet on the level of PGE[2] in young females with an age ranging from 20-25 years, Kept on the corresponding diet for 15 days. PGE[2] level was detected in peripheral blood using RIA technique of Bernard and Harold [1973]. On the basis of the findings of Daniels et al., [1967] who proved that the depressorvaso lipid found in the crude renomedullary extract of PGE[2]derived from the kidney of man [Daniels, 1971], and also Drop 1971, who proved that renal medulla synthesizes large concentrations of PGE[2]. We may illustrate our findings in the following: In case of the groups treated with high salt diet, a significant rise in the level of PGE[2] was detected. Accordingly we may consider that PGE[2] has a lowering effect on the blood pressure with regards to its natriuretic effect, while in case of the low salt diet non significant decrease occured