Benign cystic lesions of adrenal glands about 6 observations

Cystic lesions of the adrenal gland are rare. They are usually found as incidentalomas seen when abdominal ultrasound or tomodensitometry are performed. We report six cases and we underline the contribution of imagery in the diagnosis of some of the benign lesions such as epithelial cyst, cystic lymphangioma, hematic pseudocyst and hydatid cyst

[Long-term evolution of human macroprolactinomas treated with dopaminergic]

The aim of this study is to evaluate the long-term results of dopaminergic therapy in macroprolactinoma in the male. We report 5 cases of macroprolactinoma in men [age 27 to 40 years]. Four of the patients had expansive macroprolactinoma while the fifth one had an enclosed one. One patient was treated after failure of radio-surgical therapy, whereas the four other patients did not have prior surgery. Prolactin level was higher than 2500 mU/l in all cases with the presence of hypopituitarism and visual field amputation. All patients were initially treated with bromocriptin and had hormonal and pituitary CT or RMI follow up. Favourable evolution occurred in four patients with prolactin level normalisation within a few months to two years. There was a tumoral shrinkage in three cases within a period of 5 years. Bromocriptin resistance occurred in only one patient. Two years after ineffective pituitary external radiotherapy, quinagolide treatment lead to normalise prolactin levels and to reduce adenomous mass. These results emphasize the efficacy of dopaminergic therapy as first approach in macroprolactinoma in male. Nevertheless, it requires good compliance and the absence of side effects. Therefore, long acting dopaminergic or D2 receptor specific dopaminergic agents are excellent alternatives to surgery