Effect of rhPMP-2 coated implants on alveolar ridge augmentation in dogs / 대한치과보철학회지

PURPOSE: This study was aimed to evaluate the effect of rhPMP-2 coated implants on alveolar ridge augmentation in dogs. Material and METHODS: Six Beagle dogs were used in this study. Six 8.0 mm long anodized surface titanium implants were placed 5 mm into the mandibular alveolar ridge following 6 month of healing period after extraction. Each animal received three implants coated with rhBMP-2 and three uncoated control implants using the randomized split-mouth design. Radiographic examinations were undertaken i mmediately at implant placement (baseline), at weeks 4 and 8 after implant placement. The amount of bone augmentation was evaluated by measuring the distance from the uppermost point of the coverscrew to the marginal bone. Implant Stability Quotient (ISQ) values were measured i mmediately at implant placement and 8 weeks after implant placement. For the statistical analysis, Man-Whitney ranksum test and Wilcoxon signed rank test of SPSS 12.0 software were used (P = .05). RESULTS: The BMP group exhibited radiographic vertical bone augmentation about 0.6 +/- 0.7 mm at 8 weeks later while controls showed bone loss about 0.4 +/- 0.6 mm. There was significant difference among the rhBMP-2 group and controls in bone level change (P < .05). The ISQ values were significantly higher in the BMP-2 group than the control group at 8 weeks later (P < .05), while there was no significant difference at surgery. CONCLUSION: Within the limitation of this study, the rhBMP-2 coated on anodized implant could stimulate vertical alveolar bone augmentation, which may increase implant stability significantly on completely healed alveolar ridge.

Evaluation using Replica Technique on the marginal and internal fitness of zirconia cores by several CAD/CAM systems / 대한치과보철학회지

PURPOSE: This study was aimed to compare the margin and internal fitness of single anterior all-ceramic crown zirconia core made by three deferent CAD/CAM systems. MATERIAL AND METHODS: Five single zirconia cores were manufactured by three deferent CAD/CAM systems(Cerasys(R)system, KaVo Everest(R)system, Lava(TM) system). The manufactured zirconia cores were duplicated through the use of replica technique, and a replicated sample was sectioned in the center of bucolingual and mesiodistal direction to measure the marginal and internal gap. Measurement was carried out by using measuring microscope (AXIO(R)) and I-Solution(R) and analysed through the use of ANOVA. RESULTS: As for the mean marginal fitness of the zirconia core, it was 84.74 +/- 27.57 micrometer, in Cerasys(R), 80.23 +/- 21.07 micrometer in KaVo Everest(R) and 96.37 +/- 11.45 micrometer in Lava(TM), and as for the mean internal gap, it was 94.11 +/- 30.07 micrometer in Cerasys(R), 92.31 +/- 25.18 micrometer in KaVo Everest(R), and 94.99 +/- 18.74 micrometer in Lava(TM). There was no significant statistically deference among the total average gap of three systems. The internal gap in KaVo Everest(R) seemed to be smaller than Lava(TM) (P < .05). The internal gap in the incisal area was larger in all of the three systems. CONCLUSION: There was no difference in marginal fitness in Cerasys(R), KaVo Everest(R) and Lava(TM). As for the internal fitness, it was smaller in KaVo Everest(R) system than Lava(TM)system. In all of the three systems, there was a larger gap in incisal area. The marginal and internal gap was within the clinically allowed range in all of the three systems.