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São Paulo med. j ; 115(5): 1537-41, set.-out. 1997. tab
Article in English | LILACS | ID: lil-209336

ABSTRACT

To evaluate the score systems of Cassano and Sanz and suggest a new one. Design: Case series. Location: Teaching hospitals: EPM UNIFESP and Faculdade de Medicina de Botucatu. Participants: 59 patients diagnosed from 1979 to 1992. Intervention: Evaluation of clinical-laboratorial data. Measurement: Statistical comparison, uni and multivariate analysis and actuarial survival curves. Results: Cassano's system divided the patients into high and low risk (p=0.0966) while Sanz's gave high, intermediate and low risk (p=0.0108). The univariate analysis showed hemoglobin, WBC count, E/M ratio, liver size and blast percentage in BM as statistically significant. The multivariate analysis showed blast percentage in BM (p=0.004) and Hb (p=0.050) as signigicant. Our system, considering the multivariate analysis data, divided the patients into high, intermediate and low risk (p=0.0038). Conclusions: Sanz's system was more functional than Cassano's, while ours showed predictive survival value and ease of use in clinical practice.


Subject(s)
Adult , Middle Aged , Female , Humans , Adolescent , Myelodysplastic Syndromes/mortality , Prognosis , Severity of Illness Index , Aged, 80 and over , Survival Analysis , Multivariate Analysis , Retrospective Studies , Actuarial Analysis , Myelodysplastic Syndromes/blood
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