ABSTRACT
A case of Primary Non Hodgkin’s Lymphoma was diagnosed in 50 years old male patient who presented with a gastric mass. As it can not be differentiated from adenocarcinoma radiologically and progressive nature of the disease, long term follow up of the patient has been advised after the cytological diagnosis.
ABSTRACT
Aim & Objective: To study the morphological aspects of various breast lesions in patients with an apparent breast lump. To correlate the cytological findings with histopathological examination. To determine the accuracy of aspiration cytology in the diagnosis of the breast lesions. To analyse the causes of the diagnostic error and ways of overcoming them. Materials & Methods: The present study included 65 cases presenting with palpable breast lump in the outpatient department of the Shri Sayaji General Hospital Vadodara. FNA was carried out on all of them and the material studied in the Department of pathology, Medical College, Baroda, from January 2009 to September 2010. All cases were also subjected to surgical biopsy or mastectomy. Results: Out of 65 cases 21 cases were diagnosed as benign breast lesions and 44 cases were diagnosed as malignant breast lesions on cytology. On histological examination out of 21 benign lesions only one shows carcinoma while all malignant lesions were confirmed. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy was 95.2%, 100%, 100%, 95.2% and 98.4% respectively. Conclusion: In conclusion, the simplicity, rapidity, lack of morbidity, a high sensitivity, a high specificity and cost effectiveness of FNAC makes it the most valuable tool in the evaluation of the breast lesions.
ABSTRACT
Aim & Objective: To evaluate the usefulness of estimation of ADA (Adenosine deaminase) activity for etiological diagnosis of pleural effusion & to study the level of pleural fluid ADA in tuberculous & nontuberculous pleural effusion & establish cutoff limit of ADA activity. Materials & Methods: Present study was conducted in pathology department Pandit Dindayal Upadhyay Medical College Rajkot during year July 2005 to September 2007 for which we have taken 100 patients of all ages & either sex admitted in various medical wards, T.B. ward and O.P.D. Spectrophotometric method was used for ADA estimation. Results: The present study was carried out in 100 patients out of which 78 patients were of tuberculous pleural effusion & 22 cases were of Non-TB pleural effusion. There was minor difference in male & female Pleural Fluid (Both TB & Non TB) Mean ADA Level. Most of Tuberculous Effusion was in Range of 40-60 U/L ADA level (64 Pts) while Non Tuberculous effusion was between 16-20 U/L of ADA level (14 Pts). At level of 35 U/L of cut-off limit of ADA in pleural fluid sensitivity & specificity would be 94.7% & 72.7% respectively. Conclusion: The study concluded that estimation of ADA in Pleural Fluid is simple, rapid & less expensive laboratory investigation for diagnosis of tuberculous pleural effusion when diagnosis is uncertain by other investigation & it has valuable role as an adjuvant investigation to other diagnostic investigation of Tuberculosis.