ABSTRACT
PURPOSE: Myoepithelioma is a rare tumor that originates exclusively from myoepithelial cells of the salivary glands, breast and the prostate. Myoepithelioma accounts for less than 1% of all salivary gland tumors. The objective of our study is to present our experience of the infra- auricular mass which was finally diagnosed as a myoepithelioma. METHODS: A 54-year-old woman was presented with a firm, movable, slow-growing infra-auricular mass with 3 cm in diameter. MRI scans and fine needle biopsy was performed for preoperative diagnostic study. A superficial parotidectomy was preceded and removed tumor successfully. RESULTS: Histopathological study revealed a myoepithelioma of plasmacytoid type. Patient's postoperative course was uneventful without any complication and had no evidence of recurrence of tumor for 9 months follow- up period. CONCLUSION: Myoepithelioma in the parotid gland shows similar clinical courses and intraoperative finding to the pleomorphic adenoma and superficial parotidectomy was selective choice for treatment.
Subject(s)
Female , Humans , Middle Aged , Adenoma, Pleomorphic , Biopsy, Fine-Needle , Breast , Magnetic Resonance Imaging , Myoepithelioma , Parotid Gland , Prostate , Recurrence , Salivary GlandsABSTRACT
Using in situ hybridization technique with digoxigenin-labelled riboprobe, study on the expression of hsp 70 mRNA in the developing mouse brain was performed. The results obtained are as follows; 1. In embryonic day 16 group, cells with strong reactivity to hsp70 mRNA were found in spinal cord. In neuroepithelial layer lining fourth ventricle and external granular layer of cerebellum, moderate reactivity was observed. But the reactivity was weak in the forebrain including cerebral cortex, diencephalon and olfactory bulb. 2. In embryonic day 18 group, the regional pattern of hsp70 mRNA expression was similar to that of embryonic day 16 group. In medulla oblongata, however, stronger reactivity was found in the embryonic day 18 group. 3. In postnatal day 0 mice group, cells with moderate or strong reactivity to hsp70 mRNA were found in the overall area of central nervous system, Especially, cells with moderate reactivity were found in the dentate gyrus of hippocampus, and the supragranular cortical plate and subplate neocortex. 4. In postnatal day 2 mice group, cells with moderate or strong reactivity to hsp70 mRNA were found in the same pattern as in postnatal day 0 group. Further differentiation of cerebral cortex and cerebellum was found. 5. Strong expression of hsp70 mRNA was found in the areas with high rate of cell division. In general, the area of expression moved to more rostral area in central nervous system as development proceeds. Above results suggest that hsp70 play an important role in the development and differentiation of central nervous system.
Subject(s)
Animals , Mice , Brain , Cell Division , Central Nervous System , Cerebellum , Cerebral Cortex , Dentate Gyrus , Diencephalon , Fourth Ventricle , Heat-Shock Proteins , Hippocampus , Hot Temperature , HSP70 Heat-Shock Proteins , In Situ Hybridization , Medulla Oblongata , Neocortex , Olfactory Bulb , Prosencephalon , RNA, Messenger , Spinal CordABSTRACT
Since the introduction of the concept of osseointegration, the success rate of dental implant has increased dramatically. So, the uses of dental implant in the treatment of partially or fully edentulous patients have played an important role in dental rehabilitation. Regardless of high success rate of dental implant, some amounts of fixtures cannot help failing. We can classify dental implant failure according to timing, causative factor, etc. This study is focused on dental implant fixture failure, occurring during preprosthetic stage. There are various reasons that cause implant failure on this periods, such as improper patient selection, poor bone quality, and periimplantitis, etc. We investigate the survival rate of 1058 fixtures, which installed in 306 patients in our clinic from January 1997 to December 1999, according to type, sex, location, fixture length and width, using Kaplan-Meier product-limit method and to compare each other with log-rank test. Overall survival rate was 96.80%, and 33 implants failed over the preprosthetic stage. Our survey data identified posterior location of mandible as being associated with implant failure(P<0.05).
Subject(s)
Humans , Dental Implants , Kaplan-Meier Estimate , Mandible , Osseointegration , Patient Selection , Peri-Implantitis , Rehabilitation , Survival RateABSTRACT
Endoscopic balloon dilatation has provided a non-operative means of managing obstructive lesions in the gastrointestinal tract. In an infant with idiopathic hypertrophic pyloric stenosis(IHPS), the stenosis was successfully dilated with endoscopic balloon dilatation. Endoscopic balloon dilatation was performed using a 9mm endoscope and through-the-scope(TTS) balloon catheter (diameter 10 to 12mm). Dilatation was performed two times for 5 minutes. The 9mm endoscope then passed through the pylorus. There were no complications. The treatment was followed by immediate symptomatic relief. Endoscopic balloon dilatation may become a valid alternative to surgical procedures for the treatment of IHPS if good results can be confirmed in further studies.
Subject(s)
Humans , Infant , Catheters , Constriction, Pathologic , Dilatation , Endoscopes , Gastrointestinal Tract , Pyloric Stenosis, Hypertrophic , PylorusABSTRACT
PURPOSE: Helicobacter pylori (H. pylori) is recognized as the cause of primary or unexplained gastrointestinal diseases in children as well as in adults. However, it is unclear whether H. pylori causes specific clinical symptoms or diseases. Therefore, we studied the clinical manifestations associated with H. pylori infection in consecutive symptomatic children undergoing diagnostic endoscopy. METHODS: This study included 42 patients with H. pylori infection, confirmed by ELISA test, CLO test, or Warthin Starry stain of a gastric mucosa biopsy specimen. The presenting symptoms, associated disease, endoscopic findings, and hematologic features were studied in the patients retrospectively. RESULTS: The positivity of H. pylori was 15%, and increased with age. The average age of infected children was 11 years. The presenting symptoms of H. pylori infection were chronic abdominal pain (57.1%), acute abdominal pain (14.3%), pallor (11.9%), hematemesis (9.5%), and nausea/ vomiting (7.1%). The endoscopic findings were nodular gastritis (54.8%), nodular duodenitis (35.7%), duodenal ulcer (14.3%), hemorrhagic erosive duodenitis (2.4%), and normal finding (19%). The associated diseases were chronic recurrent abdominal pain (57.1%), acute gastritis (16.7%), duodenal ulcer (14.3%), and iron deficiency anemia (9.5%). CONCLUSION: H. pylori infection was associated with recurrent chronic abdominal pain, acute gastritis, duodenal ulcer, and iron deficiency anemia in children. Therefore, in patients with several gastrointestinal symptoms and iron deficiency anemia, the diagnostic and therapeutic approach of H. pylori infection is warranted.
Subject(s)
Adult , Child , Humans , Abdominal Pain , Anemia, Iron-Deficiency , Biopsy , Duodenal Ulcer , Duodenitis , Endoscopy , Enzyme-Linked Immunosorbent Assay , Gastric Mucosa , Gastritis , Gastrointestinal Diseases , Helicobacter pylori , Helicobacter , Hematemesis , Pallor , Retrospective Studies , VomitingABSTRACT
The incidence of Hypertrophic pyloric stenosis (HPS) in premature infants is rare, the presentation is not typical, and the diagnosis delayed due to uncertain diagnostic criteria in abdominal ultrasonography (US). We report two premature infants with HPS diagnosed by US and upper gastrointestinal (UGI) contrast study. Patient 1. A premature female infant (birth weight 1950 gm at 34 week's gestation) with the onset of intermittent vomiting at 9 days of age was evaluated. US was normal at 13 days of life, however, abnormal at 41 days of life (pyloric muscle length 16.5 mm). Patient 2. A premature male infant (birth weight 1470 gm at 29 week's gestation) with the onset of intermittent vomiting at 10 days of age was evaluated. US showed pylorospasm at 11 days of life, however, findings compatible with HPS at 57 days of life (pyloric muscle thickness 11 mm).UGI contrast study at 48 days of life showed similar findings in both cases. Both patients had undergone pyloromyotomy. In conclusion, the diagnosis of HPS in premature infants requires careful follow-up by US and UGI contrast study.
Subject(s)
Female , Humans , Infant , Infant, Newborn , Male , Diagnosis , Follow-Up Studies , Incidence , Infant, Premature , Pyloric Stenosis , Pyloric Stenosis, Hypertrophic , Ultrasonography , VomitingABSTRACT
Helicobacter pylori has become apparent that this organism is an etiologic agent of gastrits and peptic ulcer disease in humans. We present four cases of iron deficiency anemia, not specific causes, in 3 males and 1 female patients with Helicobacter pylori infection, who were treated with antibiotics and iron supplemented therapy. Diagnosis was confirmed by endoscopic biopsies and hematologic findings. A brief review of related literatures was also made.
Subject(s)
Female , Humans , Male , Anemia, Iron-Deficiency , Anti-Bacterial Agents , Biopsy , Diagnosis , Helicobacter pylori , Helicobacter , Iron , Peptic UlcerABSTRACT
OBJECTIVE: Recurrent abdominal pain (RAP) in children is similar to nonulcer dyspepsia of adult. Recently, microscopic inflammation and Helicobacter pylori (H. pylori) infection have been suggested as possible causes of nonulcer dyspepsia in adults. The aim was to know the clinical significance of encoscopic findings and H. pylori infection in children with RAP. METHODS: 128 children with RAP underwent upper gastrointestinal endoscopy. CLO tests were performed in 51 of 128 children for identification of H. pylori. Clinical findings were compared according to the presence or absence of mucosa abnormalities and H. pylori infections. We inquired about the improvement of abdominal pain throught OPD follow-up or phone interview. RESULTS: Upper gastrointestinal endoscopy showed abnormal macroscopic findings in 80(62.5%) of 128 children with RAP. Patients with endoscopic abnormality had the longer duration of pain than those without abnormal findings. The mean age was similar in both groups. And none of the symptoms associated with RAP correlated significantly with the endoscopic abnormality. H. pylori was confirmed in 16 of 51(31.4%) children with RAP. The mean age of children positive for H. pylori was significantly higher than that of those without H. pylori infection. Micronodularity in the antrum was found more frequently in H. pylori-poslsitive patients than in those without H. pylori infection(p=0.001). Of 128 children with RAP, 74(67.9%) showed complete loss or improvement of abdominal pain after gastrofiberscopy. The sex, age of oneset, duration of pain, gastrofiberscopic findings, and medication did not influence the outcome of children with RAP. CONCLUSIONS: Abnormal endoscopic findings are common in children with RAP and do not influence the outcome of them. H. pylori infections are not more common among children with RAP than asymptomatic children.