ABSTRACT
Objective To investigate the effects of recognition of emotional content words on event-related potentials (ERPs) of patients with major depression. Methods ERPs were recorded in 16 patients with major depression and 18 healthy subjects while they performed a visual Chinese emotional content words recognition task. The study used a word identification task consisting of 20% negative and 20% positive words as well as 60% neutral words. Results The ERPs demonstrated similar waveform (N90,P160,N250,P290,N350,P490,N650) between depression patients and normal group, but its components were different. Amplitudes of many ERPs components in patients group were significantly decreased but N250 were significantly increased in FZ and F4 as compared with those of the normal groups (P
ABSTRACT
Objective: To explore the effects of life events, automatic thoughts, social support and coping styles on the severity of depression in major depression at discharge. Methods: A cohort of 97 major depressed in-patients was assessed at discharge. The assessment included Self-Rating Depression Scale (SDS), Life Events Scale, Social Support Scale, Automatic Thoughts Questionnaire and Coping Styles Questionnaire. 100 normal controls were assessed, too.Results: Compared with the controls, the patients experienced more stressful life events in the last one year(t=2.6,P