ABSTRACT
An epidemiological field survey on snake bite was conducted on 26 randomly selected villages with a population of 18,892 in the district of Burdwan, West Bengal to assess the magnitude of the problem in a decade (1980-1989). Total number of snake bite, number of presumably poisonous snake bite and deaths due to snake bite poisoning were 307, 48 and 31 respectively. The death rate among snake bite victims was 10.09%. Males (54.72%) were bitten more than females (45.23%) and highest incidence of snake bite was found in the age group of 21-30 years and during the months of July and August. Majority of the snake bites (53%) were encountered in the lower extremities. Among the snake bite patients 201 (65.47% went to the traditional healers (ozhas) and 68 (22.14%) persons received hospital treatment, while 12 (3.09%) people neither went to the ozhas nor to hospital and 26 (8.46%) persons went to hospital after consulting the ozhas. If the present data are extrapolated for the total population of the district, average number of snake bite and death per year would be 7,857 (0.16%) and 793 (0.016%) respectively. Deaths due to snake bite per 100,000 population varied from 5.28 to 31.75 (average 16.4) over 10 years.
Subject(s)
Adolescent , Adult , Aged , Child , Child, Preschool , Extremities/injuries , Female , Humans , Incidence , India/epidemiology , Infant , Male , Middle Aged , Surveys and Questionnaires , Snake Bites/epidemiologyABSTRACT
An in vivo chloroquine resistant P. falciparum malaria case is reported from Calcutta. The resistance level being R-1. The patient responded well to pyrimethamine and sulfadoxine combination, which appears to be the drug of choice in Calcutta for choloroquine resistant P. falciparum malaria as quinine is not available.
Subject(s)
Animals , Chloroquine/therapeutic use , Developing Countries , Drug Resistance , Humans , Malaria/drug therapy , Male , Middle Aged , Plasmodium falciparum/drug effectsABSTRACT
Acute renal failure has been produced in rats with oral administration of uranyl nitrate 40 mg/kg of body weight once, and histopathological changes in the kidneys with blood biochemical values were studied by sacrificing them after 36 hours of feeding. Prostaglandin E2 in 100 micrograms/kg of body weight was orally administered to another group of rats along with uranyl nitrate 40 mg/kg of body weight once and sacrificed them 36 hours after feeding. It was found that prostaglandin E2 has some protective effect in experimental model of acute renal failure as concluded from improved histological findings and blood biochemical values.