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1.
Rev. salud pública ; 9(2): 180-193, abr.-jun. 2007. tab
Article in Spanish | LILACS | ID: lil-457928

ABSTRACT

Objetivo: Determinar la prevalencia y estimar el riesgo de obesidad para dislipidemias e hiperinsulinemia en adolescentes. Asimismo, evaluar la asociación lineal de medidas antropométricas y lípidos con insulina. Material y Métodos: Se realizó un estudio transversal comparativo entre adolescentes obesos (índice de masa corporal=IMC>percentil 95 para edad y sexo; n=120) y no obesos (IMC< percentil 85 para edad y sexo; n=120) de 10-19 años. Se aplicó una encuesta estructurada con datos sociodemográficos y antropométricos y se determinaron glucosa, insulina y perfil de lípidos. Resultados: La prevalencia de una o más dislipidemias fue de 56,6 por ciento en adolescentes c/obesidad, en comparación con 20,8 por ciento en adolescentes s/obesidad (p<.001). La hiperinsulinemia se presentó en el 50 por ciento del primer grupo mientras que en el segundo, en 4 por ciento (p<.001). La obesidad incrementó el riesgo de hiperinsulinemia con una razón de momios de (RM) de 23 (IC 95 por ciento: 8,3-68,9) y de por lo menos una dislipidemia (RM=5,0; IC95 por ciento: 2,7-9,2). El nivel de insulina se correlacionó significativamente con IMC (r=0,57), triglicéridos (r=0,57), VLDL (r=0,57), HDL (-0,37), relación cintura cadera (r=0,29), colesterol (r=0,22), y LDL (r=0,13). Conclusiones: Se evidenció a la obesidad en adolescentes como factor predisponente para el desarrollo de trastornos metabólicos y la asociación lineal de medidas antropométricas y lípidos con insulina.


Objective: Determining the prevalence and estimating the risk of obesity for dyslipidemia and hyperinsulinemia in adolescents. The existence of a linear association betweenanthropometric measures, lipids and insulin was also evaluated. Material and Methods: A comparative study was carried out amongst obese (body mass index=BMI >95th percentile for age and gender; n=120) and non-obese adolescents (BMI <85th percentile for age and sex; n=120) aged 10-19. A structured questionnaire was used for collecting anthropometric and demographic data. Glucose, insulin and lipid profiles were obtained for each adolescent. Results: Prevalence of at least one dyslipidemia was 56,6 percent among obese adolescents and 20,8 percent amongst non-obese ones (p<.001). The former registered 50 percent prevalence of hyperinsulinemia, the latter 4 percent (p<.001). Obesity increased hyperinsulinemia risk having a 23 odds ratio (8.3-68.9 95 percent CI) and for at least one dyslipidemia (OR=5,0; 2,7-9,2 95 percent CI). Insulin level significantly correlated with BMI (r=0,57), triglycerides (r=0,57), VLDL (r=0,57), HDL (-0,37), waist-hip circumference index (r=0,29), cholesterol (r=0,22), and LDL (r=0,13). Conclusions: Obesity can be considered to be a risk factor for developing metabolic disorders in adolescents. In fact, there was a linear relationship between anthropometric measurement, lipids and insulin. Prevention should focus on improving predisposing environments for obesity amongst families having children and teenagers. Emphasising life-styles and healthy behaviour is essential, as well as training and treatment options for complete care of individuals in this age-group.


Subject(s)
Adolescent , Adult , Child , Female , Humans , Male , Dyslipidemias/ethnology , Hyperinsulinism/ethnology , Metabolic Syndrome/ethnology , Obesity/ethnology , Mexico/epidemiology , Prevalence , Risk Factors
2.
Arch. cardiol. Méx ; 76(2): 151-162, abr.-jun. 2006.
Article in Spanish | LILACS | ID: lil-569149

ABSTRACT

Heart failure is one of the most important causes of death worldwide. Heart transplant is the last effective alternative when the medical and surgical treatments have failed in patients with end stage heart failure, giving them an 80% one year survival rate. Unfortunately, during the outcome, the heart transplant patients can develop complications such as graft rejection and opportunistic infections because of the use of immunosuppressive therapy. In the present article we report the experience with 33 heart transplant patients. Our program not only has successfully transplanted patients with advanced age but, for the first time in Latin America we have transplanted patients assisted with the ambulatory Thoratec TLC II system. Even with limited resources, we have managed the same complications than other heart transplant programs, our 82% one year survival rate is similar than reports in medical literature.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Heart Transplantation/statistics & numerical data , Heart Transplantation/adverse effects , Immunosuppressive Agents , Mexico , Postoperative Complications
3.
Rev. méd. IMSS ; 23(6): 479-83, nov.-dic. 1985. ilus
Article in Spanish | LILACS | ID: lil-37645

ABSTRACT

Se describe el caso de un paciente masculino de 50 años con síndrome de amiloidosis primaria y deficiencia adquirida de factor X asociada con mieloma múltiple. Las manifestaciones clínicas más importantes consistieron en infiltracion amiloide sistémica y hemorragia por mucosa gingival. El estudio integral del paciente se llevó a cabo a partir del hallazgo inicial de prolongación del tiempo de protrombina y del tiempo de tromboplastina activado. La reacción al tratamiento fue insatisfactoria, y el paciente falleció poco después de haberse logrado aparentemente la estabilización de sus complicaciones cardiovasculares y renales


Subject(s)
Middle Aged , Humans , Male , Factor X Deficiency/complications , Amyloidosis/complications , Multiple Myeloma/complications
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