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Mem. Inst. Oswaldo Cruz ; 115: e200201, 2020. tab
Article in English | LILACS, SES-SP | ID: biblio-1135281

ABSTRACT

Angiostrongylus costaricensis is the causative agent of abdominal angiostrongyliasis, a zoonotic infection that may produce severe eosinophilic enterocolitis or hepatitis in humans. Parasites are usually not released in stools and serology has an important role in diagnosis. Since cross-reactivity is demonstrated between A. costaricensis and another metastrongylid worm, A. cantonensis, we tested heterologous recombinant galectin as a probe in an immunochromatographic rapid diagnostic test (ICT-RDT) for detection of anti-A. costaricensis antibodies. Almost all (11/12) positive control sera from A. costaricensis infected patients were positive at ICT RDT. These are preliminary indications that r-galectin ICT-RDT is useful for diagnosing A. costaricensis infection.


Subject(s)
Humans , Animals , Strongylida Infections/diagnosis , Angiostrongylus cantonensis , Angiostrongylus , Immunologic Tests , Immunoassay
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