ABSTRACT
Objective:To explore the reliability and validity of Geriatric Depression Scale(GDS) when used in Chinese rural community-dwelling elderly.Methods:GDS, Social Support Rating Scale(SSRS) and Activities of Daily Living(ADL) were administrated to 412 community residents aged 60 years or more.13 of the 412 were re-tested after 20 days by telephone.Results:The result of item analysis showed that all the 30 items of GDS had met psychometric criteria.The Cronbach's ? coefficient was 0.9197, and test-retest in 20 days 0.729.GDS had acceptable discriminant validity:GDS scores negatively correlated with SSRS scores(Pearson ?=-0.459, P
ABSTRACT
Studies on the origin of the afferent acetylcholinesterase-containing fibres of the nucleus accumbens in the brain stem of 27 rats were carried out by retrograde fluorescent labeling combined with AChE histochemistry. DAPI or Pr was injected into the nucleus accumbens. The animals survived for 2.5-3 days. DFP was injected intramuscularly 6 to 8 hours before left intraventricular perfusion by 10％ formalin-containing phosphate buffer solution (0.1mol/L, pH 7.4). The frozen serial transverse sections of the brain stem were incubated in Karnovsky-Roots solution. The fluorescent retrograde labeled cells with AChE reaction-positive products were traced under OLYMPUS fluorescence microscope and light microscope simultaneously. The results were as follows: (1) On the ipsilateral side, the retrograde fluorescent labeled cells with AChE reaction-positive products were found in the following nuclei: area ventralis tegmentalis (AVT), substantia nigra (SN), nucleus raphes mesencephali caudalis(cmr), nucleus tegmenti pedunculopontinus(tpt), nucleus raphe dorsalis(dr), nucleus centralis superior (cs), nucleus reticularis tegmenti pontis(rtp), Locus ceruleus (Lc), nucleus tractus solitarus(tsol), nucleus raphe pallidus (rpa), nucleus reticularis paramedianus (rpm), subnucleus reticularis ventralis(rv), nucleus reticularis lateralis(rL). (2) On the contralateral side, a few of the above mentnioned cells were also found in AVT, SN, dr, cs, and tsol.