Prognostic factors in renal adenocarcinoma

This retrospective study of 43 cases of renal cell carcinoma showed an overall actuarial four-year survival of 52.6 percent, stage I100 percent, stage II 75 percent, stage III 40.2 percent, and stage IV 0 percent. High grade tumours gave 38.2 percent 4-year survival compared to 59 percent for low grade tumours. There was no significant difference in four-year survival of patients with either clear or granular cell types [69.6 percent and 58.1 percent respectively], while the sarcomatoid cell type had the worst prognosis [33.3 percent]. However, the histopathologic pattern did not influence survival. Survival had significantly decreased as tumour invaded perinephric fat [28 percent] or regional lymph nodes [27.3 percent]. However, renal vein involvement [34.3 percent] did not significantly affect the survival rates. Because the clinical manifestations and natural history of renal cell carcinoma are so varied, long term follow up is essential to understand better the disease and the efficacy and the available modes of therapy

9 year's experience with management of branching stones

102 patients having staghorn stones were managed, between 1975, 1984. Patients were evaluated medically, radiologically, bacteriologically and their renal function was assessed by creatinine clearance and in some cases by renogram. Different lines of management were utilized. Extended pyelolithotomy in 30 cases, Extended pyelotomy and multiple nephrotomies in 3, anatrophic nephrotomy in 23, lower polar partial nephrectomy in 15, nephrectomy in 17 and medical treatment in 19 patients. [5 patients underwent two operations]. 75 patients could be followed up using the same preoperative investigation with the addition of typing of the incecting organism. Residual stones were within the reported figures 29.5%. Infection was controlled after surgery from 80% but it increased with medical treatment. Morbidity was minimal and no mortality was reported among cases treaed surgically

Adenocarcinoma in bilharzial bladder: a retrospective study of 41 cases

Our experience with 41 patients with vesical adenocarcinoma treated between 1969 and 1983, is presented. The operative mortality was 9.5%. The 5-year actuarial survival of cases treated by radical surgery was 38.9%. The relation between treatment failures, histologic types of adenocarcinoma [Non mucin, mucin producing and mucinous] and grade is outlined