Efficacy of Aloe Vera cream versus transcutanous electrical nerve stimulation on post hemorrhoidectomy pain.

Background: Post - haemorrhoidectomy pain a major dilemma facing either patients or doctors and a little research work have been done to done to eliminate or decrease this agonizing pain. Aims & Objective: The purpose of this study was to determine the best treatment modality to decrease Post - haemorrhoidectomy pain either by natural pharmacological agent (aloe vera cram) or non-inexpensive , non-invasive physiotherapeutic modality Transcutaneous electrical nerve stimulation (TENS) as measured by visual analogue score (VAS) or post-operative analgesic consumption. Material and Methods: Thirty female patients ranging in age from 18 to 40 years and who had done open haemorrhoidectomy were classified into 3 equal groups 10 of each, Group (1): received aloe vera cream in addition to analgesic drugs , Group (2): received TENS application over acupuncture points in the hand in addition to analgesic drugs. And Group (3): served as control group and receive only analgesic drugs. Measurements of knee extension range of motion were conducted before treatment, post 5 days of treatment, and after 8 days of treatment. Results: The one way analysis of variance was used to compare VAS and postoperative analgesic consumption which revealed that both treatment groups (aloe vera and TENS) had significant (P< 0.05) decrease in VAS post-operative analgesic consumption either at 1st and 2nd week postoperatively. But aloe vera cream had highly significant (P< 0.001) decrease in VAS post-operative analgesic consumption either at 1st and 2nd week postoperatively when compared with TENS group. Conclusion: The results of this study suggest that aloe vera cream is more effective than TENS alone to decease post- haemorrhoidectomy pain.

Plasma thrombomodulin levels in patients with chronic renal failure

To evaluate the plasma soluble thrombomodulin T M levels in patients with chronic renal failure on conservative treatment and in those on hemodialysis as a new marker which reflect the extent of endothelial dysfunction with possible relation to cardiovascular complications Forty two patients with chronic renal failure together with twenty normal control subjects were allocated to this study. Patients were divided into two groups: group I of twenty patients on conservative treatment and group II of twenty two patients on hemodialysis treatment. Patients with diabetes mellitus, collagen vascular diseases, haemorrhagic diathesis and with malignancies were excluded from this study. There was significant increase in mean plasma TM levels in each group compared with normal subjects [p<0.05, p < 0.01 respecitvely]. Throm-tenodulin level was positively correlated with duration of chronic renal failure [p < 0.05]. Also, there was a positive correlation between plasma TM levels and duration of hypertension in both groups [p < 0.05; p<0.01]. Also these results may suggest that TM level can be considered as a marker for extent of endothelial damage and can reflect cardiovascular morbidity in patients with chronic renal failure