Progress in microRNA regulating apoptosis of Mycobacterium tuberculosis-infected macrophages / 中华微生物学和免疫学杂志

Apoptosis is particularly important for the body to inhibit or eliminate Mycobacterium tuberculosis ( Mtb) infection. A series of mechanisms to regulate macrophage apoptosis are triggered after macrophages are infected by Mtb. In Mtb-infected macrophages, there are differentially expressed microRNAs (miRNAs), which can directly bind to the binding sites in the 3′-untranslated region (3′ UTR) of apoptotic genes to regulate the expression of apoptotic genes and the apoptosis of macrophages through the mitochondrial or death receptor pathway. This paper reviewed the miRNAs associated with the apoptosis of Mtb-infected macrophages and the major mechanisms.

Practice on the improvement of students' self-learning ability in basic medical curriculum / 中华医学教育探索杂志

To solve problems of clinical medical students from grade 2015 and grade 2016 in self-learning awareness and habits, Weifang Medical University had taken some important measures, such as strengthening education concept, innovating teaching methods, establishing and improving teaching management system, creating a good learning environment and so on, which improved students' self-discipline, enthusiasm and ability of practice and innovation, enhanced excellent students' influence, and provided references to improve teaching quality and medical students' ability of independent learning.