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Pulmäo RJ ; 18(2): 96-101, 2009. ilus
Article in Portuguese | LILACS | ID: lil-607388

ABSTRACT

A tuberculose, causada pelo Mycobacterium tuberculosis, é a doença infecto-contagiosa, produzida por um único microorganismo, que mais causa óbitos de indivíduos adultos no mundo. O objetivo deste artigo é revisar a metodologia para a identificação do Mycobacterium tuberculosis e analisar a resistência aos medicamentos isoniazida e rifampicina, no tratamento desta doença, por métodos de biologia molecular que são cada vez mais utilizados, por sua grande sensibilidade e especificidade, apesar do custo ser ainda elevado.


Tuberculosis is an infection contagious disease caused by Mycobacterium tuberculosis and has been described as the main responsible by adult death, by the only one microorganism, in the World. The aim of this article is a review of methodology to identify the Mycobacterium tuberculosis and to analyze the resistance for isoniazid and rifampicin by biological and molecularmethods, which have been used more frequently due to high sensibility and specificity, in spite of their high price.


Subject(s)
Humans , Male , Female , Drug Resistance , Molecular Biology , Mycobacterium tuberculosis , Tuberculosis/diagnosis , Antibiotics, Antitubercular , Communicable Diseases , Isoniazid , Rifampin
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