ABSTRACT
One new flavonoid named 5, 7-dihydroxy-3,6,3'-trimethoxyflavone [1], together with eight known phenolic compounds; 3,4-dihydroxy methyl benzoate [2], 3,4-dihydroxybenzoic acid [3], isorhamnetin [4], quercetin [5], myricetin [6,], isorhamnetin-4'-O-beta-D-glucopyranoside [7], quercettn-4'-O-beta-D-g/ucopyranoside [8] and quercetin-3,4'-O-beta-D-diglucopyranoside [9] were isolated from the flowers of Cucurbita pepo L. for the first time except 3 which was previously isolated from the plant. Their structures have been established on the basis of physical, chemical and spectroscopic methods in addition to comparison with literature data and/or authentic samples. The met hanolic and ethyl acetate extracts were evaluated for their antimicrobial activity
ABSTRACT
Sixteen phenolic compounds, scopoletin [I], isoliquiritigenin 4 -methyl ether [2], luteolin 5,3 -dimethyl ether [3], luteolin 7,3-dimethyl ether [4], aureusidin 4-methyl ether [5], apigenin [6], luteolin [7], trans-ferulic acid [8], luteolin 4-O-beta-D-gluco-pyranoside [9], luteolin 7-O-beta-D-glucopyranoside [10], quercetin 3-O-beta-D-glucopyranoside [11], apigenin 7-O-neohesperidoside [12], kaempferol 3-O-rutinoside [13], quercetin 3-O-rutinoside [14], kaempferol 3-O-[2-O-D-xylopyranosyl-6-O-alpha-L-rhamnopyranosyl]-beta-D-glucopyranoside [15] and kaempferol 3-O-[2-O-D-glucopyranosyl-6-O-alpha-L-rhamnopyranosyl]-beta-D-glucopyranoside [16] were isolated from the methanolic extract of the inflorescences of Cyperus alopecuroides Rottb. for the first time. Their structures have been established on the basis of physical, chemical and spectroscopic methods in addition to comparison with literature data and/or authentic samples. The antioxidant and cytotoxic activities in addition to alpha-amylase inhibitory activity of the isolated compounds have been studied
Subject(s)
Cyperus , Biological Assay , Plants , Chromatography, Gas , AntioxidantsABSTRACT
Thirty patients complaining from insulin dependent diabetes mellitus were selected for the present study. A set of ventilatory lung function parameters was measured in each patient [N=30] and control subjects [N=10] using an electronic spirometer. The studied group showed a highly significant [p<0.001] reduction in SVC, FEV1, FEV1 / FVC, FEF 25-75% and PEFR when compared with control group. The present study showed insignificant difference in the spirometric parameters when diabetic group with duration of diabetes more than 5 years compared with diabetic group with duration of diabetes 5 years or less. Also, insignificant difference were observed in patients with blood glucose level above 200 mg/dl and those with blood glucose below 200 mg/dl. From the present study we concluded that both restrictive and obstructive ventilatory defect were observed in insulin dependent diabetes mellitus. These ventilatory disorders had no relation to both the duration and glycemic control of diabetes We recommend the periodic evaluation of pulmonary function using spirometer in insulin dependent diabetic patients even though not symptomatized and to remember that the base line is not the same as for healthy subjects
Subject(s)
Humans , Male , Female , Respiratory Function Tests , Blood GlucoseABSTRACT
The purpose of this study was to evaluate the effect of different acrylic cranial implants on serum immunoglobulins level. Fifteen patients were selected for this study. The results obtained showed insignificant change in serum immunoglobulins IgA, IgG, IgM and IgE level in patients receiving heat-processed acrylic resin cranial implants. Significant change in serum immunoglobulins [IgA, IgG, IgM and IgE] level was noticed in patients receiving autopolymerizing acrylic resin and visible light-curing resin cranial implants