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Biomedical and Environmental Sciences ; (12): 204-207, 2014.
Article in English | WPRIM | ID: wpr-270614

ABSTRACT

This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury.


Subject(s)
Animals , Male , Down-Regulation , Drugs, Chinese Herbal , Pharmacology , Heart , Microwaves , Myocardium , Cell Biology , Metabolism , Protective Agents , Pharmacology , Rats, Wistar , Receptor, Muscarinic M2 , Metabolism , Receptors, Adrenergic, beta-1 , Metabolism
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