Thyroxine and epinephrine response to reactive hypoglycaemia induced by insulin and acetyl salicylic acid in rats

48 Albino rats were classified into 4 equal groups. The 1st group received subcutaneous insulin, the second received intraperitoneal acetyl salicylic acid, the third group received both insulin and acetyl salicylic acid simultaneously. The fourth group was injected with distilled water and served as control. Animals were sacrificed and blood samples were collected 30 minutes and 60 minutes after injection. Total serum thyroxine and blood glucose levels were estimated. The results were analysed and the response of the adrenal gland and the thyroid gland to stress hypoglycaemia was evaluated

effect of 5-fluoro-uracil in heat stress situations on thermoregulation, serum cortisol and serum electrolytes

Fourty two male albino rats were divided into seven equal groups. The first group served as control, the second and third group were subjected to thermal insult for 15 minutes and 30 minutes respectively. The fourth and fifth group received 5 fluorouracil intraperitoneally. The sixth and seventh group were subjected to the combined effect of 5-F.U. and thermal insult. Rectal temperature was measured before and after experiment in all animal groups. The animals were sacrificed by decapitation and blood was collected and serum cortisol and serum electrolytes were estimated. Data were statistically analysed and the results were discussed