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Braz. j. microbiol ; 42(4): 1300-1307, Oct.-Dec. 2011. tab
Article in English | LILACS | ID: lil-614588

ABSTRACT

Causative agent in majority of VVC is Candida albicans, but infection due to non-C. albicans is common. Use of empiric antifungal therapy in Brazil due to syndromic management of vulvovaginitis could act as risk factor for increase resistance among VVC causative agents. From Mato Grosso patients, 160 with culture-proved among 404 women who had clinical symptoms of VVC, were enrolled in this study. 70 non-pregnant women and 90 pregnant women were included. Candida albicans was the most prevalent, representing 72.9 percent in the non-pregnant group and 92.3 percent in the pregnant group. Differences in species distribution were noted between the two groups, being C. parapsilosis the second more prevalent species among non-pregnant women. Susceptibility testing revealed high susceptibility to fluconazole (except for C. krusei), itraconazole, ketoconazole, and amphotericin B regardless the species (C. albicans, C. parapsilosis, C. tropicalis, C. glabrata, C. krusei) analyzed.


Subject(s)
Humans , Female , Antifungal Agents , Antifungal Agents/analysis , Candida albicans/isolation & purification , Candidiasis, Vulvovaginal/therapy , Diagnostic Techniques and Procedures , Disease Susceptibility , Drug Resistance, Microbial , Vulvovaginitis/therapy , Methods , Microbial Sensitivity Tests , Patients , Prevalence , Methods
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