ABSTRACT
Objective To explore the clinical significance of renal artery ultrasound hemodynamic index and advanced oxidation protein product(AOPP)in evaluating the renal function level in preeclampsia pregnant women. Methods Seventy two cases of preeclampsia pregnant women in the Central Hospital of Zhumadian City were divided into mild group(39 cases)and se-vere group(33 cases)according to the pathogenetic condition,and 35 healthy pregnant women who were hospitalized and deliv-ered in the same period were selected as the control group. Ratio of systolic to diastolic(S/ D),pulsation index(PI),resistance index(RI)of renal artery were detected by color Doppler ultrasound in all patients. The levels of plasma AOPP and serum creati-nine(Cr),uric acid(UA),cystatin C(Cys C),blood urea nitrogen(BUN)were detected. The results among the three groups were analyzed. Results The S/ D,PI,RI of renal artery,the levels of plasma AOPP and serum Cr,Cys C,BUN in the severe group were significantly higher than those in the mild group and the control group(P <0. 05). The S/ D,PI,RI of renal artery,the levels of plasma AOPP and serum Cys C in the mild group were significantly higher than those in the control group(P < 0. 05). There was no significant difference in the level of serum Cr and BUN between the mild group and the control group(P >0. 05). There was no significant difference in the serum UA level among the three groups(P >0. 05). The results of Pearson correlation analysis showed that the S/ D,PI,RI of renal artery and AOPP were positively correlated with the level of Cys C(r =0. 557,0. 621,0. 597, 0. 608;P <0. 05),but they was not correlated with the level of serum Cr,UA and BUN(r =0. 133,0. 159,0. 215;P >0. 05). The S/ D,PI,RI of renal artery were positively correlated with the level of plasma AOPP(r = 0. 582,0. 639,0. 633;P < 0. 05). Con-clusion Detection of renal artery hemodynamic parameters and AOPP level can help to predict renal function in preeclampsia pregnant women.
ABSTRACT
Objective To explore the clinical value of measurement of cerebral blood flow volume by color Doppler flow imaging in patients with cerebral infarction.Methods One hundred and thirty six patients with cerebral infarction in Central Hospital of Zhumadian City from February 2015 to February 2017 were selected as CI group,and 40 non-CI patients in the corresponding time period were chosen as control group.The end diastolic flow velocity,systolic peak systolic velocity,resistance index,and mean flow velocity of the vertebral artery and internal carotid arteries of all the patients were detected by color Doppler flow imaging,and anterior and posterior circulation and total cerebral blood flow were calculated.At the same time,through the color Doppler flow imaging results of the CI group,the patients were divided into anterior circulation blood-supply infarction (anterior circulation group,101 cases) and posterior circulation blood-supply infarction(posterior circulation group,35 cases) according to the blood-supply scope.The patients in the anterior circulation group were divided into cortical branches group (32 cases),perforating branche group (55 cases) and watershed group (14 cases) according to the feeding artery,while the patients in the posterior circulation group were divided into distal infarction group (15 cases),mid-range infarction group (12 cases) and proximal infarction group (8 cases).The cerebral blood flow volume were compared among the groups.Results The end diastolic flow velocity of vertebral artery in the CI group was significantly lower than that in the control group,and the resistance index was significantly higher than that in the control group (P ＜ 0.05).The carotid intravascular diameter and the end diastolic flow velocity in the CI group was significantly lower than those in the control group,and the resistance index was significantly higher than that in the control group (P ＜ 0.05).There was no significant difference in the vertebral artery diameter,the peak velocity of internal carotid artery and vertebral artery between the CI group and the control group(P ＞0.05).The right vertebral artery blood flow,the left and right internal carotid artery blood flow,cerebral blood flow of the anterior circulation and the total cerebral blood flow in the CI group were significantly lower than those in the control group,and cerebral blood flow of the posterior circulation was significantly higher than that in the control group (P ＜ 0.05).The cerebral blood flow of the anterior circulation in the anterior circulation group was lower than that in the posterior circulation group(P ＜0.05),while the cerebral blood flow of the posterior circulation was significantly higher than that in the posterior circulation group(P ＜0.05).There was no significant difference in the total cerebral blood flow between the anterior circulation group and the posterior circulation group(P ＞ 0.05).There was no significant difference in the cerebral blood flow of anterior circulation and posterior circulation,the total cerebral blood flow among the cortical branches group,the perforating branche group and the watershed group(P ＞ 0.05).Also there was no significant difference in the cerebral blood flow of anterior circulation and posterior circulation,the total cerebral blood flow among the distal infarction group,the mid-range infarction group and the proximal infarction group(P ＞0.05).Conclusion The hemodynamics indexes and cerebral blood flow of vertebral artery and internal carotid are well analyzed and evaluated by color Doppler flow imaging,and the color Doppler has a certain clinical values on the diagnosis for CI.