ABSTRACT
Background: Anemia is one of the most common medical disorder during pregnancy and one of the important cause of maternal death in the third world countries. A sufficient supply of iron is also required for the proper development of the fetus and newborn baby. During pregnancy, iron deficiency and iron deficiency anemia (IDA) increase the risk of preterm birth and low birth weight. Iron is essential for the development of the fetal brain and the newborn’s cognitive abilities. Pregnant women receive oral iron prophylaxis have better iron status and are less likely to develop IDA. The aim of the study was to evaluate the effects of prophylactic oral iron therapy in pregnant women in terms of rise of haemoglobin level.Material & Methods:The present study was conducted at the department of obstetrics and gynecology, US-Bangla Medical College & Hospital, Dhaka, Bangladesh, from January 2020 to June 2021 with a sample size of 100 pregnant women. All the participants were non-anemic at the time of inclusion, and a proper follow-up was done. All the women were supplied with 60 mg dose of elemental iron prophylactic. During follow up haemoglobin level was measured and serum ferritin levelwas measured when anemia was found. The collected data were analyzed by using the Statistical Package for Social Science (SPSS-24) for windows version 10.0.Results:During the first follow-up, 89% were found non-anemic, 9% were mildly anemic and 2% were moderately anemic. S ferritin levels of the 11 anemic participants showed that 36.30% had <15 ng/mL ferritin levels, and 63.64% had 15-150 ng/mL ferritin levels. During the second follow-up, 86% were non-anemic, 1% was severely anemic, 4% were moderately anemic and 9% were mildly anemic. S. ferritin level test showed that among the 14 anemic women, 35.72% had <15 ng/mL, 57.14% had 15-150 ng/mL, and 7.14% had >150 ng/mL serum ferritin levels. During third follow up at 34-36 weeks, 81% were non-anemic, 1% were moderately anemic, 8% had mild anemia. S. ferritin levels of 9anamic women showed that 3 women (33.33%)had <15 ng/mL and 6 women (66.67 %) had between 15-150 ng/mL.Conclusions:Pregnancy produces relatively high iron demand. Iron requirements cannot be met merely through dietary iron intake. Even prophylacyic 60 mg elemental iron giving may not be sufficient to prevent maternal anemia. Regular follow up and monitoring is essential during whole pregnancy for better management of the patients.
ABSTRACT
Background: Hypertensive disorder is one of the commonestmedical complications of pregnancy. It is assumed that serumuric acid elevation is a specific laboratory finding for thedisease.Objectives: To assess the effect of raised Serum uric acidlevel on outcome of pregnancy in cases of PIH (PregnancyInduced Hypertension).Methods: A Prospective study was conducted to pregnantpatients (between 28-40 weeks of pregnancy with PIH). Total100 patients were selected, who were separated into twogroups. Those who had Serum uric acid level more than6mg/dl (67 participants) are classified as Group A and thosewho had Serum uric acid level less than 6mg/dl (33participants) are classified as Group B.Results: Age of PIH patients were within 16-40 years. Theserum uric acid was significantly elevated in all the patients.Concentration of Serum uric acid is much higher in Eclampsiagroups, which is 4.5-12.0 mg/100ml (7.36 ± 2.17), incomparison to Preeclampsia patients, which is 2.6-9.6mg/100ml (6.28 ± 1.64). Comparing maternal outcome withSerum uric acid level between group A and group B patients,percentage of PPH and Abruptio placenta was higher in groupA than group B. In addition, Postpartum eclampsia, HELLPsyndrome and Pulmonary oedema were present in group A(each 2 in number); but these complications are not found ingroup B. In perinatal outcome, the better consequence wasobserved in group B in case of birth weight, intrauterine growthretardation, still birth and neonatal death rate. There wasstatistical significant association between Serum uric acid andbirth weight of group A & B (p= 032).Conclusion: The degree of hyperuricemia increases with theseverity of preeclampsia. Perinatal mortality was markedlyincreased when maternal serum uric acid concentration wereraised. Serum uric acid was an important indicator for maternalcomplications and prognosis of fetus.