ABSTRACT
Preeclampsia is a hypertensive, multi-system disorder of pregnancy that significantly contributes to maternal and fetal/neonatal morbidity and mortality. It is found that Mgnesium sulfate injection is associated with lower apgar score and poor muscle tone. There are some confounding factors as meconium stained, birth asphyxia . Thus to ascertain whether poor muscle tone and poor APGAR score is solely due to Magnesium or other reasons, we have done the study
ABSTRACT
Protein/creatinine ratio of a single voided urine specimen may have a role in the management of ambulatory women with suspected PIH, which necessitates further research in the field. We did a systematic review of the literature and multivariate meta–analysis with the objective of determining the diagnostic accuracy of the protein to creatinine ratio compared with 24 hour urine collection for the detection of significant proteinuria in patients with suspected pre–eclampsia and to look at their ability to predict adverse outcome for mother and baby & to find out its co–relation with disease severity. The spot urinary protein /creatinine ratio can be used as an alternative to 24–hours urinary protein excretion in patients with PIH.
ABSTRACT
Background:Oral manifestations of HIVdisease is important, as they affect the quality of life and useful marker of disease progression . Aims:The study was designed to search for the oral lesions in seropositive patients and their possible prognostic value.Methods: This prospective observational study included 211 new cases withconsecutive two ELISAtest positive attended in OPD . Relevant investigations and biopsies were taken to confirm clinical diagnosis . The causal relationship between prevalence of oral lesions and demographical variants,therapeutic regimen and CD4 count were evaluated.The technique and protocol were approved by the ethics committee of the institution.Results :Out of 211 patients ,75 (35.44%) patients had detectable oral lesion with male predominance . Majority belonged to the age group of 21- 30 years . All the variants ofcandidiasis were seen. Pseudo membranous type was most frequently observed .Herpes simplex is the commonest viral infection. One case of hairy leukoplakia was seen. Necrotizing ulcerative periodontitis (NUP) was observed in four cases. Aphthous ulcer were seen in eight cases.Conclusions :In our series cases with orofacial involvement had CD4 count <600 cells/ml. Majority of the patients had CD4 < 200 cells/ml
ABSTRACT
Interest in vulvar disorder increased in last few years and needs multidisciplinary approach. Aim and objective:To study the clinical presentation, evaluate the spectrum of factors influencing the pathology and outline its prevention.Methods :Aprospective observational study was conducted on 40 patients presenting with vulvar lesions from February 2016 to August 2016 on Wednesday out patients department . Cases were selected after taking proper history, clinical examinations and necessary investigations with histopathological examination and treated with regular follow up. Patients from 12 years onwards with vulvar lesions were included in this study. We excluded known cases of vulvar carcinoma, diabetes mellitus, immuno-compromised; post radiation vulvo-vaginitis, carcinoma cervix and paediatric age group patients from our study. The technique and protocol of this study design were approved by the ethical committee of the institutionResult: Out of 3686 OPD attendee 40 (1.09%0 patients were in the study group, the incidence of vulvar lesions was 1.09%. Majority were aged between 20-30 years and 40-50 years (12/40 or 30%). The mean age of the patients was 40.4 years. Seventy percent of the women were of lower socio-economic status and 30% of patients were belong to middle socio-economic status and no woman of upper socio-economic status were reported. Vulvar abscess (25%), Bartholin's Cyst (15%), Lichen Sclerosis atrophicus (15%), Squamous cell carcinoma (10%), Squamous papilloma (10%) and Squamous cell hyperplasia (10%) were the frequent presenting vulvar lesions.Discussion:The spectrum of vulvar lesions is a wide ranging .Infection was the main stay of aetiology. Poor hygiene and overall lack of awareness about sexually transmitted diseases are frequently seen among the patients. So, our health care providers need to educate women regarding vulvar hygiene in the form of health awareness programme by all sectors. and motivate them to maintain proper hygiene and seek early help from physicians.