1.
Egyptian Journal of Medical Laboratory Sciences. 2003; 12 (1): 1-11
in English
| IMEMR
| ID: emr-61822
Subject(s)
Humans , Male , Female , Hepatitis B, Chronic , Cytokines , Hepatitis C, Chronic , Interleukin-2 , Interleukin-4 , Interleukin-10 , Interferon-gamma , Liver , Biopsy , RNA, Messenger , Liver Function Tests
2.
New Egyptian Journal of Medicine [The]. 2002; 27 (Supp. 1): 45-54
in English
| IMEMR
| ID: emr-60320
ABSTRACT
To investigate the effects of ribavirin on hepatitis C virus [HCV] specific T-helper cell responses and the expression of interleukin-12 receptor-beta-1 and beta-2 chains on CD4+ T cells, peripheral blood mononuclear cells from 56 patients with proven chronic hepatitis C were incubated with or without ribavirin [0.1 mug/ml]. The results suggested that ribavirin induces up-regulation and differentiation of CD4+ T cells through the up-regulation of interleukin-12 receptor beta-2 chain