Revaluation of the Hutchinson's Sign / 대한피부과학회지

BACKGROUND: The appearance of skin lesions at the dermatome of the nasociliary nerve in herpes zoster involving the ophthalmic nerve (Hutchinson's sign) was associated with an increased incidence of ocular complications. OBJECTIVE: This study is aimed to revaluate the clinical usefulness of the original concept of Hutchinson's sign in herpes zoster involving the ophthalmic nerve. METHODS: A total of 70 patients with herpes zoster, involving the ophthalmic nerve, were enrolled in this study at the medical center, Daegu Catholic University from December 2004 to July 2006. Statistical analysis using chi-sqaure test in verified the relationship between the clinical parameters and the development of ocular lesions (p<0.05). RESULTS: Statistical analysis showed that the presence of underlying disease, severity of pain, severity of skin lesions and Hutchinson's sign were the predictive factors of the development of ocular lesions. A strong relationship formed between the Hutchinson's sign and the development of ocular lesions [Relative risk: 6.769 (Confidence interval 95%: 2.310~19.838)]. CONCLUSION: Hutchinson's sign may be a useful predictive factor in the development of ocular lesions in the herpes zoster involving the ophthalmic nerve.

A Case of Nevus of Nanta

Nevus of Nanta is a pigmented nevus associated with secondary ossification. We describe a case of nevus of Nanta with no evidence of Albright's hereditary osteodystrophy. A 26-year-old Korean woman presented with a small asymptomatic brownish nodule on the right forehead. Histopathologic examination revealed nests of nevus cells in the dermis. Round ossification was in the base of intradermal nevus.

A Case of Papuloerythroderma of Ofuji which Responded to Treatment with Cyclosporine / 대한피부과학회지

Papuloerythroderma of Ofuji is an uncommon dermatological disorder of unknown etiology and is characterized by a pruritic eruption of widespread confluent papules in vast sheets over the skin, but spares the skin folds (the so-called 'deck-chair' effect). We present a case of a patient with papuloerythroderma of Ofuji of unknown cause. Treatment with oral and topical corticosteroids, antihistamines, and narrow-band UVB phototherapy proved to be ineffective in helping the condition but considerable clinical improvement was obtained with cyclosporine.

Two Cases of Pyoderma Gangrenosum Associated with Crohn's Disease / 대한피부과학회지

Pyoderma gangrenosum has been described in association with a wide variety of disorders, including Crohn's disease, ulcerative colitis, myeloproliferative disease, monoclonal gammopathy, and Behcet's disease. Herein, we report two cases of pyoderma gangrenosum associated with Crohn's disease. The first case was a 24-year-old female who presented with multiple, necrotizing ulcers on the scalp, which is a rarely affected site. The other case was a 30-year-old female who presented with erythema nodosum on the lower leg initially, and subsequent rapidly-progressive ulcerating lesions then developed at the previous biopsy and intravenous injection sites. In both cases, the colonoscopic findings were consistent with Crohn's disease. The lesions improved with a combined therapy of systemic steroids, sulfa drugs and topical 0.03% tacrolimus ointment.

Generalized Actinic Granuloma with Ocular Involvement,Subsequent Development of Temporal Arteritis / 대한피부과학회지

A 63-year-old Korean man presented with generalized, asymptomatic, discrete papules and coalescent annular plaques for one year. Interestingly, the patient complained of conjunctival congestion, concurrently with aggravation of the skin lesion. Histopathologic findings of the skin lesion and conjunctiva revealed giant cells engulfing fragmented elastic fibers, and a diagnosis of actinic granuloma with ocular involvement was made. Ten months later, the patient revisited with a two-week history of bilateral temporal headache, neck pain, intermittent jaw claudication, and blurred vision. Biopsy of the temporal artery confirmed the clinical diagnosis of temporal arteritis. Both actinic granuloma and temporal arteritis show similar pathologic process, and this case supports the hypothesis that actinically degenerated elastic tissue is likely to be the antigenic basis of actinic granuloma of the skin and temporal arteritis.

A Case of CREST Syndrome with Extensive Calcinosis Cutis / 대한피부과학회지

CREST syndrome is an indolent form of systemic sclerosis and refers to the manifestations of calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasias. We report a typical case of CREST syndrome in a 67-year-old woman, who presented with extensive, hard, calcified nodules and plaques on her shins, fingers, pelvis, and shoulder.

Cutaneous Angiomyolipoma

Angiomyolipoma is a benign tumor, almost exclusively of the kidney, that is often associated with tuberous sclerosis. Cutaneous location is extremely rare. We report a case of cutaneous angiomyolipoma which occurred on the retroauricular area. A 57-year-old man presented with an asymptomatic mass on the retroauricular area. Although the clinical similarity to an epidermal or pilar cyst was striking, the histopathologic picture was distinctive. The tumor was a well-circumscribed subcutaneous mass composed of a mixture of smooth muscle, vascular spaces, and mature fat covered by a thin fibrous membrane.

A Case of Genital Porokeratosis / 대한피부과학회지

We report a case of 45 year old man with a porokeratosis of Mibelli on his scrotum. He presented with 4 year history of an annular pruritic skin lesion on his scrotum. The skin lesion showed an initial rapid growth, but then stabilized without further change. Histologic examination revealed a typical cornoid lamella consisting of packed parakeratotic cells. Porokeratosis in the genital area is rare, but can occur in a generalized form with genital area involvement or a localized form confined to the genital area.

A Case of Neonatal Tinea Capitis / 대한의진균학회지

Tinea capitis in the neonatal period is extremely rare. To our knowledge, there have been only a few reports of neonatal tinea capitis in the Korean dermatologic literature. We report an additional case of neonatal tinea capitis caused by Microsporum canis. The patient was successfully treated with oral griseofulvin.

Poliosis Circumscripta Associated with Halo Nevus of the Scalp / 대한피부과학회지

Poliosis circumscripta describes a localized patch of white hair due to deficiency of melanin in the hair follicles. It is a feature of various conditions such as piebaldism, Vogt-Koyanagi-Harada syndrome, tuberous sclerosis, vitiligo, recent herpes zoster infection, or overlying a scalp neurofibroma. We report a rare case of poliosis circumscripta associated with halo nevus of the scalp. A 24-year-old woman presented with a 10 year history of an asymptomatic, pinkish nodule on the scalp which had overlying poliosis. On histopathological examination, dermal nevus cells were observed and the hair follicles of the depigmented patch were found to be devoid of pigment.

A Case of Actinic Lichen Planus Mimicking Melasma / 대한피부과학회지

No abstract available.

A Case of Palmar Filiform Hyperkeratosis / 대한피부과학회지

Palmar filiform hyperkeratosis is characterized by multiple, tiny, keratotic projections on the palms. This disease has been associated with various underlying benign or malignant diseases. We present 69 year-old-man with 8-year history of palmar filiform hyperkeratosis. After development of skin lesions, he was diagnosed as having rheumatoid arthritis, hypertension, chronic renal failure, multiple renal and hepatic cysts, and multiple adenomas in the stomach and colon, in turn. Histopathologic examination revealed a compact parakeratotic column on an absent or thin granular layer. Treatment with 15% salicylic acid ointment under occlusion was partially effective.