ABSTRACT
Objective To understand the measures and effects of schistosomiasis elimination in Wujin District,Changzhou City,so as to provide the reference for other similar areas. Methods The data of schistosomiasis prevention and control were collected and analyzed in Wujin District,Changzhou City from 1995 to 2015. Results From 1995 to 2015,the accumulated ar-ea for investigating Oncomelania hupensis snail habitats was 15934.01 hm2 in Wujin District,and the accumulated area with snail habitats was 34.61 hm2,but no schistosome-infected snails were found. The area of snail control by molluscicides was 234.59 hm2,and the area of snail control by environmental reform was 84.48 hm2 in 18 key points. There were 259.3 thousand person-times receiving the examinations for schistosomiasis,and there were 17314 head of livestock receiving the examinations for schistosomiasis,but no schistosome-infected cases were found. There were 2042 person-times receiving the extensive chemo-therapy. The popularizing rate of sanitary toilets was 99.25％in the whole district. The awareness rate of schistosomiasis control knowledge was 98.08％and the formation rate of proper behaviors was 97.82％in the population. Conclusions In Wujin Dis-trict,the aim of schistosomiasis elimination has been performed through the active control measures. However,there are still so-cial and natural risk factors of re-endemic of schistosomiasis,and therefore,the schistosomiasis monitoring work still should be strengthened.
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the significance of trophinin expression in human oocytes and preimplantation embryos.</p><p><b>METHODS</b>The expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope.</p><p><b>RESULTS</b>Human oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05).</p><p><b>CONCLUSION</b>Trophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.</p>