ABSTRACT
Thrombocytopenia is a common extrahepatic manifestation of chronic viral hepatitis C. Many mechanisms are implicated in its genesis, specially the immunological factor. Several ways of treatment were used with a temporal efficiency. We reported an observation of a 62 year old female-pateint of chronic viral hepatitis C, who developed a severe thrombocytopenic purpura. Steroid therapy was ineffective. Treatment of such cases is difficult as association of immunosuppressive therapy increases the platelet count, but lad to severe hepatocellular insufficiency due to its negative effect on the hepatic function. Using other molecules as the immunoglobulines or interleukin II constitute a promising alternative way of treatment
Subject(s)
Humans , Female , Purpura, Thrombocytopenic , Hepatitis, ChronicABSTRACT
During the year 1993, 144 eesophageal manometries were carried out. The indications are dysphagia [40%] check-up for gastro-esophageal reflux [25%], scleroderma [17%], pseudo-anginal thoracic pain [16%]. The esophageal manometry was normal in 35% of cases. It disclosed hypotonia in 24%, achalasia in 15%, esophageal scleroderma in 6%, a digly esophagus in 2% essential hypertonia of cardia in 2% and non classificable motor disorders in 17%.The positive diagnosis is more significant when the esophageal manometry is indicated in dysphagia