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Objective To explore the safety and effectiveness of 3D reconstruction in thoracoscopic posterior basal segmentectomy (S10).Methods Between March 2018 to September 2018,14 patients underwent thoracoscopic anatomical resection of the posterior basal segment of the lung (S10).Results Of the 14 patients,including 5 males and 9 females,age (52.2 ± 5.3) years,size (1.1 ± 0.6) cm,6 left S10 and 8 right S10.The number of pathological type of microinvasive adenocarcinoma,benign nodule,and metastatic carcinoma was 12,1,and 1 cases.The average preoperative planning time was (44.9 ± 5.7) min,and the average operation time was (134.8 ±26.3)min.The blood loss was (25.5 ±4.1)ml,with (8.1 ± 2.7) lymphadenectomy,no positive metastasis.The coincidence rate of 3D reconstruction and intraoperative anastomosis in the tumor location,B10,A10,and V10 were 100％ (14/14),100％ (14/14),93％ (13/14) and 71％ (10/14).The median duration of chest tube insertion was (2.3 ±2.1)day.The incidence of postoperative complications was 21％ (3/14),including 7％ (1/14) of air leakage,7％ (1/14) of arrhythmia,14％ (2/14) of pulmonary infection,and 14％ (2/14) of operation.All the cutting edge was ＞ 2 cm.There was no perioperative death,no conversion to thoracotomy or lobectomy.The mean follow-up time was (8.1 ±2.2)months.There were no recurrence,metastasis or death in the 14 patients.One patient had chronic cough and no hemoptysis.Conclusions Preoperative 3D reconstruction make the anatomic thoracoscopic posterior basal segmentectomy (S10) safer and more effective.
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Objective@#To explore the safety and effectiveness of 3D reconstruction in thoracoscopic posterior basal segmentectomy (S10).@*Methods@#Between March 2018 to September 2018, 14 patients underwent thoracoscopic anatomical resection of the posterior basal segment of the lung (S10).@*Results@#Of the 14 patients, including 5 males and 9 females, age (52.2±5.3)years, size (1.1±0.6)cm, 6 left S10 and 8 right S10. The number of pathological type of microinvasive adenocarcinoma, benign nodule, and metastatic carcinoma was 12, 1, and 1 cases. The average preoperative planning time was (44.9±5.7)min, and the average operation time was (134.8±26.3)min. The blood loss was (25.5±4.1)ml, with (8.1±2.7) lymphadenectomy, no positive metastasis. The coincidence rate of 3D reconstruction and intraoperative anastomosis in the tumor location, B10, A10, and V10 were 100%(14/14), 100%(14/14), 93%(13/14) and 71%(10/14). The median duration of chest tube insertion was (2.3±2.1)day. The incidence of postoperative complications was 21%(3/14), including 7%(1/14) of air leakage, 7%(1/14) of arrhythmia, 14%(2/14) of pulmonary infection, and 14%(2/14) of operation. All the cutting edge was >2 cm. There was no perioperative death, no conversion to thoracotomy or lobectomy. The mean follow-up time was (8.1±2.2)months. There were no recurrence, metastasis or death in the 14 patients. One patient had chronic cough and no hemoptysis.@*Conclusions@#Preoperative 3D reconstruction make the anatomic thoracoscopic posterior basal segmentectomy (S10) safer and more effective.
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<p><b>OBJECTIVE</b>To compare the perioperative complications between Ivor-Lewis approach and McKeown approach in minimally invasive esophagectomy and gastric tube reconstruction for the treatment of middle and lower thoracic esophageal cancer.</p><p><b>METHODS</b>Retrospective analysis of clinical data was performed on 288 patients with middle and lower thoracic esophageal cancer who underwent completely minimally invasive esophagectomy by one surgical team in Fujian Medical University Union Hospital from December 2010 to March 2014. Among the 288 patients, 103 patients underwent combined laparoscopic and thoracoscopic esophagectomy and intrathoracic esophagogastric anastomosis using a transoral anvil(Orvil)(Ivor-Lewis group, 2-incision) and 185 patients underwent combined laparoscopic and thoracoscopic esophagectomy and cervical anastomosis(McKeown group, 3-incision). Patients were stratified by surgical approach and perioperative outcomes were compared between the two groups.</p><p><b>RESULTS</b>There were no statistical differences between two groups in intra-operative blood loss, conversion to open, extubation time, time to resume oral intake, postoperative hospital stay, the median number of lymph nodes resected. The operation time of Ivor-Lewis group was significantly shorter than that of McKeown group [(283.4±32.0) min vs. (303.6±43.7) min, P=0.003). The hospital cost of Ivor-Lewis group was significantly higher than that of McKeown group [(76 492±18 553) yuan vs. (68 923±17 331) yuan, P<0.01]. There were no statistical differences between two groups in chylothorax, delayed gastric emptying, atrial fibrillation, postoperative bleeding, admission to ICU, short-term postoperative mortality (P>0.05). The total postoperative complication morbidity of Ivor-Lewis group was significantly lower than that of McKeown group(16.5% vs. 31.4%, P<0.01). Ivor-Lewis group had lower pulmonary complication(8.7% vs. 25.9%, P<0.01), anastomotic leakage(1.9% vs. 13.0%, P<0.01), anastomotic stricture (0% vs. 4.9%, P<0.05), recurrent laryngeal nerve injury(1.0% vs. 7.0%, P<0.05).</p><p><b>CONCLUSION</b>Ivor-Lewis approach is associated with less postoperative complications, but higher cost as compared to McKeown approach in the treatment of middle and lower thoracic esophageal cancer.</p>
Subject(s)
Humans , Anastomosis, Surgical , Anastomotic Leak , Blood Loss, Surgical , Esophageal Neoplasms , General Surgery , Esophagectomy , Methods , Laparoscopy , Length of Stay , Minimally Invasive Surgical Procedures , Methods , Operative Time , Postoperative Complications , Plastic Surgery Procedures , Methods , Retrospective StudiesABSTRACT
OBJECTIVE: To evaluate the effect of ?3 Adrenoceptor (?3-AR) antagonist SR59230A(SR) on cardiac function and expression of ?3-AR in rats with heart failure. METHODS: A total of 85 male Wistar rats were enrolled: 8 were as-signed to control group, and 77 were established into heart failure model and then 20 rats that modelled successly assigned ran-domly to placebo group or SR group, with placebo group intraperitoneally injected with normal saline and SR group with SR. The echocardiogram, hemodynamics, and expression of ?3-AR in rats after 7-week treatment were followed. RESULTS: In SR group compared with placebo group, shortening fraction, ejection fraction, left ventricular end systolic pressure, dp/dtmax and dp/dtmin were significantly higher (P
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The results showed that the survival rate increased by 40. 0%-80. 0% ,the level of 6-keto PGP1? increased by 38. 3%-79. 2%,and the product of TXB2 decreased by 24. 5%-58. 8% by the purified oil of Anguilla japonica (POAJ) 139. 6,279. 2,558. 4 and 1116. 8?g ? g-1 in mice. The ratio of 6-keto-PGF1? to TXB2 were enhanced markedly,in which the ratioes were 1.12 (control group) ,2. 05,2. 65,3. 57 and 4. 89 (drug group).