1.
Journal of International Pharmaceutical Research
;
(6): 213-216, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-845952
ABSTRACT
It is difficult to est isosorbide 5-mononitrate in biological specimen due to its unsignificant UV absorption and thermal instability. Therefore, uarious methods such as HPLC, GC-ECD, GC-MS and HPLC-MS/MS were established to meet the needs of assay sensitivity and specificity. Research progress in the chromatography is reviewed in this paper.