ABSTRACT
With the characteristics of fast prototyping and personalized manufacturing, 3D-printing (three-dimensional printing) is an emerging technology with promising applications for orthopedic medical devices. It can complete the process of medical devices with complex shape which can not be completed by conventional fabrication process. At present, a variety of orthopedic medical devices manufactured by 3D printing technology, has been approved for marketing, and their use has been proved to be beneficial. 3D bioprinting in this area has also made a few breakthroughs. However, many challenges still remain to be addressed as well. In this study, the research status, as well as the development of the 3D-printing technology in the field of orthopedic medical devices is elaborated.
Subject(s)
Printing, Three-Dimensional , Bioprinting , Commerce , ResearchABSTRACT
Objective To study the expression and significance of miR-608 in ameloblastoma (AB).Methods Quantitative stem-loop RT-PCR was used to detect the expression of miR-608 in 26 cases of human AB (AB group) and 17 cases of peritumoural tissues (control group).The differences in miR-608 levels between the control group and the AB groups,namely,primary AB and recurrent AB,were evaluated.In addition,miR-608 levels in AB cases with different clinical and pathological characteristics were compared.Results The expression level of miR-608 in the AB group was significantly lower than that in the control group (P ＜ 0.05).Additionally,the relative expression level of miR-608 in the primary AB group was significantly lower than that in the recurrent AB group (P ＜ 0.05).There were no significant differences between the miR-608 expression levels with respet to age,gender,or pathological type (P ＞ 0.05).Conclusions The expression of miR-608 in human AB tissue is significantly decreased,which may be related to the recurrence of the tumor.