1.
Indian J Exp Biol
;
1980 Jan; 18(1): 6-8
Article
in English
| IMSEAR
| ID: sea-55620
2.
Indian J Physiol Pharmacol
;
1979 Apr-Jun; 23(2): 115-20
Article
in English
| IMSEAR
| ID: sea-107457
ABSTRACT
Toxicological study was carried out in rats with chloroform-soluble fraction of the nuts of Semecarpus anacardium to determine its safe non-toxic dose. The fraction produced toxicity at all levels tested (50-400 mg/kg) but the extent of toxicity was found dose-dependent. At lower doses this fraction induced partial growth inhibition over 36 days and higher doses proved fatal within 6 days. It was observed that 230 mg/kg caused 50% mortality in rats and this value is 1380 mg/m2 when expressed for body surface area. This work will be of some use in the cancer chemotherapy study of the fraction.
Subject(s)
Animals , Behavior, Animal/drug effects , Body Weight/drug effects , Lethal Dose 50 , Male , Nuts , Plant Extracts/toxicity , Plants, Medicinal , Rats , Time Factors
3.
Indian J Cancer
;
1977 Dec; 14(4): 320-4
Article
in English
| IMSEAR
| ID: sea-50934
Subject(s)
Adolescent , Adult , Antineoplastic Agents/therapeutic use , Child , Copper/blood , Drug Therapy, Combination , Female , Hodgkin Disease/blood , Humans , Male
4.
Indian J Cancer
;
1977 Dec; 14(4): 313-6
Article
in English
| IMSEAR
| ID: sea-50560