Electrophysiologic Finding of Retinitis Pigmentosa Inversus and Differential Diagnosis from Peripapillary Choroidal Dystrophy

The authors found 3 cases of retinitis pigmentosa inversus who had characteristics that age of onset is between fifth and sixth decade, retinal lesion was seen around the optic disc and along the retinal vascular arcade, margin is discrete, and peripheral retina is morphologically normal. The authors performed routine ophthalmic examination, fluorescein angiography, electroretinography, electro-oculography. Fluorescein angiogram of retinitis pigmentosa inversus showed diffuse hyperfluoresce due to retinal pigment epithelium atrophy and partical hypofluoreseenee due to choriocapillary atrophy. Characteristic electroretinogram findings were moderate decrease of rod function and mild decrease of cone function. The authors also experienced 1 cases of peripapillary choroidal dystrophy and could differentiate it from retinitis pigmentosa inversus. Peripapillary choroidal dystrophy showed similar that of retinitis pigmentosa inversus in electroretinogram test, but showed diffuse and typical hypofluo rescence due to choriocapillary and retinal pigment epithelium atrophy according to the retinal lesion.

The Effect of Cyanoacrylate Glue on Wound Healing of The Cornea Following Rabbit Radial Keratotomy

The authors performed conventional radial keratotomy(RK) in one eye(Keratotomy group) and RK with cyanoacrylate glue in the other eye(Glue group) for 5 rabbits and compared the diopteric changes between before and four weeks after operation. The refractory power(mean+/-SD) of the cornea meassured with keratometer before the RK was 51.53 +/- 0.77 diopter(D) in Keratotomy group and 51.98 +/- 0.84D in Glue group. It was reduced four week after RK by 4.73 +/- 1.94D and 7.15 +/- 1.46D. respectively. The change of refractive power between two groups showed a statistically significant difference(p0.05). Histologic examination was performed with 4 eyes of 2 rabbits 4 week after RK. It was found in both groups that same pattern of epithelial plug and irregulaly oriented collagen fibers in stroma. However, the epithelial plug was more prominent in RK group than in Glue group. In conclusion, it was found that that RK with cyanoacrylate glue was more effective in reduction of keratometic diopter than keratotomy alone and the reason seemed to be a decreased epithelial plug in a keratotomy wound.