ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of serum beta-human chorionic gonadotropin (β-HCG) on days 9 (d9) and 11 (d11) after fresh embryo transfer (ET) and frozen-thawed embryo transfer (FET) in predicting the pregnancy outcomes.</p><p><b>METHODS</b>A total of 227 fresh ET and FET cycles performed at the Center of Reproductive Medicine, Qingyuan People's Hospital between Dec, 2012 and Feb, 2014 were analyzed. The data of serum β-HCG levels on d9 and d11 after fresh ET and FET cycles and the pregnancy outcomes were reviewed, and the ROC curve was constructed to determine the optimal cut-off level of serum β-HCG level for predicting pregnancy outcomes.</p><p><b>RESULTS</b>According to pregnancy outcomes, the cycles were divided into non-pregnancy group (group A), biochemical pregnancy group (group B), and clinical pregnancy group (group C). Significant differences were found between the mean serum β-HCG levels measured on d9 and d11 in all the 3 groups (P<0.01). The cycles in group C were further divided into 5 subgroups with single pregnancy (C1), twin pregnancy (C2), early abortion (C3), ectopic pregnancy (C4), or intrauterine pregnancy complicated with ectopic pregnancy group (C5), and all the 5 subgroups showed significant differences in β-HCG measurements between d9 and d11 (P<0.01). On d9 after ET and FET, the optimal cut-off level of serum β-HCG was 49.05 IU/L for predicting for clinical pregnancy, and was 105.15 IU/L for predicting twin pregnancy; the two corresponding cut-off levels of serum β-HCG on d11 was 51.2 IU/L and 241.75 IU/L, respectively.</p><p><b>CONCLUSION</b>The absolute serum β-HCG level on d9 and d11 after fresh ET and FET allows an accurate diagnosis of pregnancy and helps in the prediction of the pregnancy outcomes.</p>
Subject(s)
Female , Humans , Pregnancy , Chorionic Gonadotropin, beta Subunit, Human , Blood , Embryo Transfer , Fertilization in Vitro , Pregnancy Outcome , ROC Curve , Retrospective StudiesABSTRACT
Objective To summarize the experience of operation treatment of severe mitral stenosis associated with small left ventricle.Methods The clinical data of 115 patients with severe mitral stenosis received mitral valve replacement (MVR) were retrospectively analyzed.According to whether associated with small left ventricle,they were divided into small left ventricle group (61 cases) and non-small left ventricle group (54 cases).The postoperative early complication rate and mortality rate between two groups were compared.Results The postoperative early complication rate and mortality rate in small left ventricle group was higher than that in non-small left ventricle group [14.75％ (9/61) vs.7.41％ (4/54),55.74％ (34/61) vs.25.93％(14/54)],there was significant difference(P ＜ 0.05).Conclusions The positive and effective perioperative management and correct intraoperative decision is key to reduce the incidence of early postoperative complications and mortality after MVR surgical in patients with severe mitral stenosis associated with small left ventricle.
ABSTRACT
Objective To study the feasibility,efficacy,and safety of MRI-guided percutaneous cryoablation for the treatment of hepatic carcinoma. Methods From January to September 2008,27 cases of hepatic carcinoma were treated with MRI-guided percutaneous cryoablation with Cryo-Hit system via two cycles of freezing-thawing. During the procedure,MRI showed the expansion of ice globe wrapping the tumor. Ten days after the freezing treatment,TACE was carried out in 5 cases. Results MRI-guided percutaneous cryotherapy were completed successfully in all of the cases. In 26 patients (96.3%),expanded ice globe wrapping the tumor was detected by MRI,showing a dark zone with clear margin. Only in one patient,the tumor was wrapped. The patients were followed up for 1 to 12 months (mean,3.5 months),during which the level of AFP decreased to a normal value in 14 cases (51.9%),continued to increase in 1 cases,and increased after an reduction in 12 cases (44.4%). The patients received more than one times of re-examination by imaging,which showed completed necrotic tumor tissues or no confirmed living tumors in 14 cases (51.9%); and incomplete tumor necrosis or living tumor lesions in 13 (48.1%). No severe complications occurred in this series.Conclusions MRI-guided percutaneous cryoablation is feasible,effecitve and safety for hepatic carcinoma.