Les caracteristiques hematologiques des syndromes myelodysplasiques lors de la premiere presentation: etude retrospective de 14 cas

The haematological characteristics of 14 cases of primary my‚lodysplastic syndromes [MDS] were reviewed at initial presentation on the bases of FAB classification. The distribution according to the 5 types of MDS is: AR = 3 patients, ASAI = 3 patients, AREB = 4 patients, AREB-T-3 patients and LMMC = 1 patient. Two third of the patients are over 60 years. The anemia is present at all of patients, while the leukopenia and the thrombopenia are noted respectively in 28.4% and 53.8% of cases. The pancytop‚nia is noted in 28.4% of cases. The cytologic and histologic study of the bone marrow constitute they key of diagnosis. The bone marrow is normocellular or hyper- cellular in all of cases. The dyserythropoiesis is marked in the cases of AR and ASAI with Perls coloration strongly positive in the last [52% of total erythroblast]. In the other hand, the dysgranulopoiesis is important in the cases of AREB, AREB-T and LMMC, with expressive medullar blastosis [10% to 20%]